… Identification of a translocation with quinacrine fluorescence in a patient with acute leukemia…
transcription factors and epigenetic modulators promote leukemic transformation. To date, …

… in chronic myelogenous leukemia (CML) and ALL. Furthermore, cytogenetic analysis is now
… important tool in diagnosis and prognostication of acute leukemias. Specific chromosome …

… consideration in the cytogenetic diagnosis of a patient in whom leukemia is suspected is …
patient’s bone marrow or peripheral blood. If aberrations are present, this means that the patient …

… in the routine diagnostic workup of leukemias and many large … leukemia patients’ risk
stratification banding cytogenetic analysis continue to play essential roles in leukemia diagnostics. …

… Subgroup analysis demonstrated that the three cytogenetically … the importance of diagnostic
cytogenetics as an independent … a clinical diagnosis of acute promyelocytic leukemia (APL) …

… An important factor in the diagnosis of acute lymphoblastic leukemia (ALL) is that karyotype
is an independent prognostic indicator, with an impact on the choice of treatment. Outcome is …

… by chromosome banding analysis and FISH in our laboratory, which is the central reference
laboratory for cytogenetic and molecular diagnostics within the AML Study Group Ulm. All …

… shifts with morphologic and cytogenetic findings at relapse in patients with AML (48, 49). In
the … diagnosis and relapse in patients with AML for whom complete morphologic, cytogenetic, …

… and metaphase cytogenetics in every case, in which acute leukemia is … In 50–70% of patients
with acute leukemias acquired clonal … The cytogenetic results at diagnosis provide the most …

… In 1960, Nowell and Hungerford [Citation5] discovered the presence of an abnormal G-group
chromosome in the leukemic cells from patients affected by CML for the first time. …