… IL-6 pathway. Here, we discuss the emerging roles for IL-6 family members in infection, chronic
inflammation, … therapeutic strategies designed to manipulate these cytokines in disease. …

… signalings of this family cytokines and their impacts on the inflammatory responses or disorders.
… of this family cytokines and their impacts on the pathogenesis of inflammatory diseases. …

… of a broad variety of inflammatory cytokines. Numerous studies have implicated that
inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the …

… of the body to stop the inflammatory response will end in uncontrolled destruction of …
inflammatory diseases, allergies or cancer. The interleukin (IL)-1 family includes a set of cytokines, …

… The IL-1agonist family, IL-1α, IL-1β and IL-1, are unique in the cytokine families. Each is
initially synthesized as precursor molecules without a signal peptide. After processing by the re…

… of inflammatory diseases, and a number of therapeutic programmes targeting these family
… cells, and role in inflammation of these and the less-characterized family members, IL-17B, …

… cytokine immunobiology is central to the development of rational therapies for destructive
inflammatory diseases … The classical interleukin-1 (IL-1) family cytokines, IL-1α and IL-1β, as …

… -1 family cytokines play in sterile inflammatory diseases. … diseases (Figure 1). In this review
we focus on the pivotal role of IL-1 family cytokines in various sterile inflammatory diseases. …

… -36 family as an important mediator of inflammatory diseases in various tissues has expanded
our knowledge surrounding the role of the broader IL-1 family in health and disease while …

… in several inflammatory diseases such as obesity, atherosclerosis, cancer, viral and
parasite infections, and auto-inflammatory syndromes as well as liver diseases. Inflammation …