Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer
SA Jones, BJ Jenkins - Nature reviews immunology, 2018 - nature.com
… autoimmune conditions with drugs that target the IL-6 pathway. Here, we discuss the emerging
roles for IL-6 family members in infection, chronic inflammation, autoimmunity and cancer …
roles for IL-6 family members in infection, chronic inflammation, autoimmunity and cancer …
IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases
X Song, Y Qian - Cellular signalling, 2013 - Elsevier
… , metabolic disorders and cancer. Interleukin (IL)-17 … , we highlight the up-to-date knowledge
of this family cytokines and their impacts on the pathogenesis of inflammatory diseases. …
of this family cytokines and their impacts on the pathogenesis of inflammatory diseases. …
Function and regulation of IL‐1α in inflammatory diseases and cancer
A Malik, TD Kanneganti - Immunological reviews, 2018 - Wiley Online Library
… diseases and cancer. While the regulation and function of IL-1β and other IL-1 cytokines
has … understanding of regulation and function of IL-1α in inflammatory diseases and cancer. …
has … understanding of regulation and function of IL-1α in inflammatory diseases and cancer. …
IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
N Unver, F McAllister - Cytokine & growth factor reviews, 2018 - Elsevier
… IL-6 is a critical cytokine in acute phase response and involved in the pathogenesis of …
inflammatory diseases including cancer. Studies have highlighted that levels of IL-6 and its family …
inflammatory diseases including cancer. Studies have highlighted that levels of IL-6 and its family …
More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancer
T Putoczki, M Ernst - Journal of leukocyte biology, 2010 - academic.oup.com
… members of this cytokine family. In this review, we focus on IL-11 as a member of the IL-6
family of cytokines that has been implicated recently in linking inflammation to cancer within the …
family of cytokines that has been implicated recently in linking inflammation to cancer within the …
The interleukin (IL)-1 cytokine family–Balance between agonists and antagonists in inflammatory diseases
… of the body to stop the inflammatory response will end in uncontrolled destruction of …
inflammatory diseases, allergies or cancer. The interleukin (IL)-1 family includes a set of cytokines, …
inflammatory diseases, allergies or cancer. The interleukin (IL)-1 family includes a set of cytokines, …
Cytokines in inflammatory disease
… abolished the IL-6 levels [44]. … IL-6 can be a predictor of survival in head and neck cancer
[45]. Yet, it often remains unclear if IL-6 is only correlative to cancer or rather essential in cancer …
[45]. Yet, it often remains unclear if IL-6 is only correlative to cancer or rather essential in cancer …
Inflammatory cytokines in the pathogenesis of cardiovascular disease and cancer
… inflammatory cytokines are also well known to induce numerous chronic inflammatory disorders…
Recent study has reported that increased release of cytokines, including TNF-α, IL-6 and …
Recent study has reported that increased release of cytokines, including TNF-α, IL-6 and …
SOCS proteins in immunity, inflammatory diseases, and immune-related cancer
… Signaling by cytokines needs to be tightly controlled in order … inflammatory conditions,
increased susceptibility to infectious … IL-6 family of cytokines that act via STAT3, notably including …
increased susceptibility to infectious … IL-6 family of cytokines that act via STAT3, notably including …
Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
SI Grivennikov, M Karin - Annals of the rheumatic diseases, 2011 - ard.bmj.com
… Another inflammation-linked cancer in which inflammatory cytokines have a significant role
… of liver cancer. HCC often develops in association with chronic liver inflammation caused by …
… of liver cancer. HCC often develops in association with chronic liver inflammation caused by …
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