Cytokine regulation of natural killer cell effector functions
NW Zwirner, CI Domaica - Biofactors, 2010 - Wiley Online Library
… natural cytotoxicity and critical players for the control of viral infections and tumor growth, recent
investigations unraveled more widespread functions for the natural killer (… Cytokines play …
investigations unraveled more widespread functions for the natural killer (… Cytokines play …
[HTML][HTML] Sarcopenia, obesity, and natural killer cell immune senescence in aging: altered cytokine levels as a common mechanism
CT Lutz, LBS Quinn - Aging (Albany NY), 2012 - ncbi.nlm.nih.gov
… is required for the development and survival of natural killer (NK) lymphocytes. We review
the … We posit that increased adipokine and decreased IL-15 levels during aging constitute a …
the … We posit that increased adipokine and decreased IL-15 levels during aging constitute a …
The biology of human natural killer-cell subsets
MA Cooper, TA Fehniger, MA Caligiuri - Trends in immunology, 2001 - cell.com
… Owing to their early production of cytokines and chemokines, … subset is more naturally cytotoxic
and expresses higher levels of Ig… cytokines following activation of monocytes, but has low …
and expresses higher levels of Ig… cytokines following activation of monocytes, but has low …
Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines
N Halama, M Braun, C Kahlert, A Spille, C Quack… - Clinical cancer …, 2011 - AACR
… that natural killer (NK) cells are generally absent in CRC of all stages. We provide evidence
that this absence is not dependent on simple lack of one of the known factors: local cytokines…
that this absence is not dependent on simple lack of one of the known factors: local cytokines…
A novel role for interleukin‐18 in human natural killer cell death: high serum levels and low natural killer cell numbers in patients with systemic autoimmune diseases
K Shibatomi, H Ida, S Yamasaki… - Arthritis & …, 2001 - Wiley Online Library
… In the present study, we evaluated the relationship between serum cytokine levels and …
Our data reveal that increased levels of cytokines correlate with reduced numbers of NK …
Our data reveal that increased levels of cytokines correlate with reduced numbers of NK …
Psychosocial modulation of cytokine-induced natural killer cell activity in older adults
BA Esterling, JK Kiecolt-Glaser… - Psychosomatic medicine, 1996 - journals.lww.com
… In addition, we would expect at least some modulation of the effect of the cytokines on the
E-NK cells in this study compared with NK cells in PBL samples treated with both cytokines in …
E-NK cells in this study compared with NK cells in PBL samples treated with both cytokines in …
Natural killer cells in antiviral defense: function and regulation by innate cytokines
CA Biron, KB Nguyen, GC Pien… - Annual review of …, 1999 - annualreviews.org
… Natural killer (NK) cells are populations of lymphocytes that can beactivated to mediate
significant levels of cytotoxic activity and produce highlevels of certain cytokines and chemokines…
significant levels of cytotoxic activity and produce highlevels of certain cytokines and chemokines…
Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset
MA Cooper, TA Fehniger, SC Turner… - Blood, The Journal …, 2001 - ashpublications.org
… cytokines (monokines), stimulate natural killer (NK) cells to produce immunoregulatory
cytokines … In this report, it is shown that CD56 bright NK cells produce significantly greater levels …
cytokines … In this report, it is shown that CD56 bright NK cells produce significantly greater levels …
[HTML][HTML] IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells
R Parihar, J Dierksheide, Y Hu… - The Journal of clinical …, 2002 - Am Soc Clin Investig
… The use of PBMCs in our coculture assay might provide a more accurate picture of the cytokine
levels to be found within the tumor microenvironment following systemic administration of …
levels to be found within the tumor microenvironment following systemic administration of …
Cytokine production by CD16–CD56bright natural killer cells in the human early pregnancy decidua
S Saito, K Nishikawa, T Morii, M Enomoto… - International …, 1993 - academic.oup.com
… cytokines (13 -16), it seems likely that activated CD16-CD56brisht NK cells in the decidua
produce cytokines, and that these cytokines … In the present study, we examined cytokine mRNA …
produce cytokines, and that these cytokines … In the present study, we examined cytokine mRNA …
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