Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells
P Pandiyan, J Zhu - Cytokine, 2015 - Elsevier
… -box transcription factor (T-bet) and CXCR3 [19]. Th17 like T regs express Foxp3, retinoic …
Such effector like Foxp3+ T reg cells producing pro-inflammatory cytokines are readily found at …
Such effector like Foxp3+ T reg cells producing pro-inflammatory cytokines are readily found at …
Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease
N Eastaff-Leung, N Mabarrack, A Barbour… - Journal of clinical …, 2010 - Springer
… by regulatory T cells (T reg ), a population of CD4 + T cells that control immune responses
in the gut by inhibiting the proliferation and effector functions of other T cells [3]. T reg are …
in the gut by inhibiting the proliferation and effector functions of other T cells [3]. T reg are …
Regulatory T cells and Foxp3
AY Rudensky - Immunological reviews, 2011 - Wiley Online Library
… Furthermore, deletion of self antigen-specific thymocytes as well as activation and clonal
expansion of, and cytokine production by peripheral antigen-specific T cells were not affected …
expansion of, and cytokine production by peripheral antigen-specific T cells were not affected …
Foxp3, regulatory T cell, and autoimmune diseases
JH Tao, M Cheng, JP Tang, Q Liu, F Pan, XP Li - Inflammation, 2017 - Springer
… site of Foxp3 [75], both possibly receding Treg cell suppressive function. Inflammatory
cytokines can also modulate regulatory T cell … expression of the Foxp3 transcription factor [104]. …
cytokines can also modulate regulatory T cell … expression of the Foxp3 transcription factor [104]. …
Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 …
… The decreased ratio of Ag-specific effector vs regulatory T cells upon treatment with RA …
in the effector T-to-regulatory T cell ratio is mainly due to a decrease of effector T cells in RA-…
in the effector T-to-regulatory T cell ratio is mainly due to a decrease of effector T cells in RA-…
Regulatory T cells and inhibitory cytokines in autoimmunity
M Bettini, DAA Vignali - Current opinion in immunology, 2009 - Elsevier
… Foxp3 + regulatory T cells (T regs ) contribute significantly to the maintenance of
peripheral tolerance, but they ultimately fail in autoimmune diseases. The events that lead to …
peripheral tolerance, but they ultimately fail in autoimmune diseases. The events that lead to …
CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation–mediated apoptosis of effector CD4+ T cells
P Pandiyan, L Zheng, S Ishihara, J Reed… - Nature …, 2007 - nature.com
… Here we show that T reg cells induced apoptosis of effector CD4 + T cells in … cytokine
deprivation–induced apoptosis responder T cells provided a prominent contribution to T reg cell …
deprivation–induced apoptosis responder T cells provided a prominent contribution to T reg cell …
Cytokine therapy with interleukin-2/anti–interleukin-2 monoclonal antibody complexes expands CD4+ CD25+ Foxp3+ regulatory T Cells and attenuates development …
TN Dinh, TS Kyaw, P Kanellakis, K To, P Tipping… - Circulation, 2012 - Am Heart Assoc
… to chronically expand this T cell population, by complexing the cytokine interleukin-2 …
regulatory T cells, markedly increasing their numbers. Other interleukin-2–responsive lymphocytes …
regulatory T cells, markedly increasing their numbers. Other interleukin-2–responsive lymphocytes …
The role of the transcription factor Foxp3 in the development of regulatory T cells
JM Kim, A Rudensky - Immunological reviews, 2006 - Wiley Online Library
… and a role for TCR- and cytokine-mediated signals in regulation of Foxp3 expression. … specific
marker for regulatory T cells to date, our laboratory generated Foxp3 reporter (Foxp3 GFP ) …
marker for regulatory T cells to date, our laboratory generated Foxp3 reporter (Foxp3 GFP ) …
An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell–suppressive function and therapeutic efficacy
JS Do, A Visperas, YO Sanogo, JJ Bechtel… - Mucosal …, 2016 - nature.com
… We report that interleukin (IL)-27, an IL-12 family cytokine … Foxp3 + regulatory T cells (Tregs)
are key regulators of immune … Proinflammatory cytokines can directly alter Treg function …
are key regulators of immune … Proinflammatory cytokines can directly alter Treg function …
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