Lack of interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice

H Kirii, T Niwa, Y Yamada, H Wada… - … , and vascular biology, 2003 - Am Heart Assoc
… — Atherosclerosis is considered to be a chronic inflammatory disease and many cytokines
participate in the development of atherosclerosis… of the proinflammatory cytokines secreted by …

Targeted delivery of anti-inflammatory cytokine by nanocarrier reduces atherosclerosis in Apo E−/-mice

M Kim, A Sahu, Y Hwang, GB Kim, GH Nam, IS Kim… - Biomaterials, 2020 - Elsevier
… the cytokine in the atherosclerosis lesions. IL10 delivered by NC was bioactive and reduced
the production of pro-inflammatory cytokinecytokine delivery for preventing atherosclerotic

Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice

S Vorlova, M Koch, HD Manthey… - Thrombosis and …, 2017 - thieme-connect.com
… V Leiden mice, augments atherosclerotic lesion formation (4, 5)… for normal haemostasis in
humans and mice, FXII has crucial … atherosclerosis in low density lipoprotein receptor-deficient …

Genetic modifiers of atherosclerosis in mice

JW Knowles, N Maeda - Arteriosclerosis, thrombosis, and vascular …, 2000 - Am Heart Assoc
studies. Finally, we discuss some of the current limitations of mouse models of atherosclerosis
and … For example, finding a specific cytokine in atherosclerotic plaques but not in normal …

[PDF][PDF] Inflammation in atherosclerosis

P Libby, Y Okamoto, VZ Rocha, E Folco - Circ J, 2010 - cardiacos.net
… in the form of proinflammatory Th1 cytokines, such as IFN-γ, and Th2 cytokines, such as IL-10…
atherosclerosis. Studies in mice and in humans show that inflammation drives all phases of …

[HTML][HTML] Inflammation in atherosclerosis

S Taleb - Archives of cardiovascular diseases, 2016 - Elsevier
… The majority of T cells in mouse and human atherosclerotic plaques … cytokines, CD4+ T
lymphocytes differentiate into a Th1, Th2 or Th17 lineage. Besides producing specific cytokines

The immune system in atherosclerosis

GK Hansson, A Hermansson - Nature immunology, 2011 - nature.com
… Targeted deletion of genes encoding costimulatory factors and proinflammatory cytokines
results in less disease in mouse models, whereas interference with regulatory immunity …

Attenuation of experimental atherosclerosis by interleukin-19

S Ellison, K Gabunia, SE Kelemen… - … , and vascular biology, 2013 - Am Heart Assoc
atherosclerotic disease process based on the predominance of Th1 lymphocytes and their
cytokines in both human and mouse atherosclerotic … smaller number of studies focus on the …

Molecular link between cholesterol, cytokines and atherosclerosis

D Kaul - Molecular and cellular biochemistry, 2001 - Springer
… Recent studies addressed to understand the role of … [51] revealed that atherosclerotic lesions
in mice could be reduced … in the atherosclerotic plaques of apo-‘E’-knockout mice and this IL…

Act locally, act globally—microbiota, barriers, and cytokines in atherosclerosis

N Kurilenko, AR Fatkhullina, A Mazitova, EK Koltsova - Cells, 2021 - mdpi.com
… Genetic or pharmacological studies in micecytokines have been shown to regulate
atherosclerosis [2], here we focus on cytokines which have an established role in atherosclerosis