[HTML][HTML] Circadian clock genes as promising therapeutic targets for bone loss

Y Qin, Z Chen, JJ Wu, ZY Zhang, ZD Yuan… - Biomedicine & …, 2023 - Elsevier
The circadian clock regulates many key physiological processes such as the sleep–wake
cycle, hormone release, cardiovascular health, glucose metabolism and body temperature. …

MicroRNAs: promising therapeutic targets for the treatment of pulmonary arterial hypertension

K Yuan, M Orcholski, X Tian, X Liao… - Expert Opinion on …, 2013 - Taylor & Francis
Introduction: MicroRNAs (miRNAs) are small noncoding RNAs that not only regulate gene
expression during normal development but can also be active players in several diseases. To …

Vitamin D resistant genes–promising therapeutic targets of chronic diseases

KL Milan, R Jayasuriya, K Harithpriya, M Anuradha… - Food & Function, 2022 - pubs.rsc.org
Vitamin D is an essential vitamin indispensable for calcium and phosphate metabolism, and
its deficiency has been implicated in several extra-skeletal pathologies, including cancer …

Regulation of toll-like receptor (TLR) signaling pathways in atherosclerosis: from mechanisms to targeted therapeutics

M Jin, J Fang, J Wang, X Shao, S Xu, P Liu… - Acta Pharmacologica …, 2023 - nature.com
… In recent years, TLRs have gained special attention as promising therapeutic targets for AS.
As the quest for increasingly effective medications is crucial, we discuss the involvement of …

[HTML][HTML] Interaction of arterial proteoglycans with low density lipoproteins (LDLs): From theory to promising therapeutic approaches

H Kang, J Lu, J Yang, Y Fan, X Deng - Medicine in Novel Technology and …, 2019 - Elsevier
… and its interaction with LDLs, seeking promising therapeutic targets more specifically. … and
cytokines [23], which gradually accumulates during the development of atherosclerosis and …

Kv1. 3 Potassium Channels: Promising Therapeutic Targets in Hematological Malignancies

T Lowinus, T Bose, L Simeoni… - Journal of Cellular …, 2020 - scientificarchives.com
Voltage-gated Kv1. 3 potassium channels control the membrane potential, cellular activation
and cell death. Kv1. 3 channels have been extensively studied in autoimmune disorders …

[HTML][HTML] The role of immune mechanisms in abdominal aortic aneurysm: could it be a promising therapeutic strategy?

R Dinc - Acta Cardiologica Sinica, 2023 - ncbi.nlm.nih.gov
cytokines are involved in macrophage activation, VSMC apoptosis, and direct destruction of
aortic walls. In AAA, both Th1 cytokines and Th2 cytokines are … promising therapeutic targets

[HTML][HTML] Quest for new biomarkers in atherosclerosis

Y Cho, Á Baldán - Missouri medicine, 2013 - ncbi.nlm.nih.gov
… are promising therapeutic targets to manage patients at risk of developing atherosclerosis. …
MIF activates the expression of various proinflammatory cytokines and chemokines. This …

Sphingosine-1-phosphate-specific G protein-coupled receptors as novel therapeutic targets for atherosclerosis

Y Okamoto, F Wang, K Yoshioka, N Takuwa… - Pharmaceuticals, 2011 - mdpi.com
… and cytokine secretion in monocyte-derived macrophages, and eNOS inhibition and cytokine
… , S1P receptors, particularly S1P 2 , are promising therapeutic targets for atherosclerosis. …

Cytokines in atherosclerosis

JWE Moss, DP Ramji - Cytokine effector functions in tissues, 2017 - Elsevier
… There is therefore a need to develop a better understanding of the role of cytokines during …
cytokines during atherosclerosis plaque formation. Therapeutic avenues for targeting cytokine