… potential of these receptors as promising therapeutic targets to treat a wide … atherosclerosis
development, trigger through CLEC9A, the downregulation of the anti-inflammatory cytokine …

… However, novel promising therapeutic targets have been recently identified. This review
summarizes the current knowledge of pathomechanisms involved in aortic valve calcification …

… by the action of cytokines. Macrophages play a pivotal role in atherosclerosis and represent
promising therapeutic targets. Current therapies against atherosclerosis are associated with …

… pathways as promising therapeutic targets. … atherosclerosis process by their ability to
incorporate oxLDL to form foam cells and to secrete several matrix-degrading proteases, cytokines …

… is one of the promising therapeutic targets for diabetic … cytokines, and elevation of serum
C-reactive protein (CRP) level. These features are also seen in DN and atherosclerosis …

… The interaction of adaptive and innate immune cells in the pannus contributes not only to
an overwhelming release of cytokines but also to local secretion of pro-inflammatory alarmins. …

… This review demonstrates that NRG4 and its receptors are promising therapeutic targets for
the treatment of socially significant obesity-associated pathologies. The review contains nine …

… We highlight the pathways to cellular injury, thereby identifying promising therapeutic
targets… Cultured adipocytes and tissue macrophages release inflammatory cytokines that are …

… role of OPN in the pathogenesis of cardiac fibrosis, a common theme in various types of
cardiovascular diseases, could hold the key to the identification of promising therapeutic targets …

… In summary, ANGPTLs are promising therapeutic targets as monoclonal antibodies, ASO,
gene editing and compounds targeting ANGPTL3/4/8 have become important drug candidates …