S100-alarmins: potential therapeutic targets for arthritis
J Austermann, S Zenker, J Roth - Expert opinion on therapeutic …, 2017 - Taylor & Francis
… The interaction of adaptive and innate immune cells in the pannus contributes not only to
an overwhelming release of cytokines but also to local secretion of pro-inflammatory alarmins. …
an overwhelming release of cytokines but also to local secretion of pro-inflammatory alarmins. …
Endothelial dysfunction sustains immune response in atherosclerosis: potential cause for ineffectiveness of prevailing drugs
S Akhtar, A Sharma - International Reviews of Immunology, 2022 - Taylor & Francis
… Moreover, the role of various cytokines and chemokines in atherosclerosis is discussed in-depth
elsewhere [Citation27]. Briefly, cytokine IL-8 expressed by activated/dysfunctional ECs …
elsewhere [Citation27]. Briefly, cytokine IL-8 expressed by activated/dysfunctional ECs …
[HTML][HTML] Interleukin-17a: A New Therapeutic Target in Hypertension?
CJB Jacome, PAF Uribe, JLO Ochoa, SSS Salcedo… - 2023 - biomedscis.com
… of interleukin 17A (IL-17A), also known as effector cytokine of Th17 cells, is distinguished,
which is currently recognized as one of the most promising therapeutic targets [16]. …
which is currently recognized as one of the most promising therapeutic targets [16]. …
From endothelium to lipids, through microRNAs and PCSK9: a fascinating travel across atherosclerosis
D D'Ardes, F Santilli, MT Guagnano, M Bucci… - High Blood Pressure & …, 2020 - Springer
… on the scene of atherosclerosis and their interaction is … molecules thereby promoting
atherosclerosis. Inflammation is … may facilitate the genesis of atherosclerosis, independently of its …
atherosclerosis. Inflammation is … may facilitate the genesis of atherosclerosis, independently of its …
[HTML][HTML] Comparative roles of IL-1, IL-6, IL-10, IL-17, IL-18, 1L-22, IL-33, and IL-37 in various cardiovascular diseases with potential insights for targeted …
M Abubakar, HF Rasool, I Javed, S Raza, L Abang… - Cureus, 2023 - ncbi.nlm.nih.gov
… , atherosclerosis, and heart failure (HF). ILs have emerged as promising therapeutic targets
for … IL-17A is another inflammation-promoting cytokine linked to atherosclerosis and CVD …
for … IL-17A is another inflammation-promoting cytokine linked to atherosclerosis and CVD …
Vascular actions of adipokines: molecular mechanisms and therapeutic implications
… A-FABP expression in adipose tissue are causally associated with obesity-related inflammation
and vascular dysfunction, both adipokines represent promising therapeutic targets for …
and vascular dysfunction, both adipokines represent promising therapeutic targets for …
[HTML][HTML] Nutraceuticals as therapeutic agents for atherosclerosis
… with a chronic inflammatory response mediated by a range of cytokines [4,5]. The lipid-rich …
in the pathogenesis of atherosclerosis are all promising therapeutic targets, major success …
in the pathogenesis of atherosclerosis are all promising therapeutic targets, major success …
[HTML][HTML] Novel insights and new therapeutic potentials for macrophages in pulmonary hypertension
Y Zuo, B Li, M Gao, R Xiong, R He, N Li, Q Geng - Respiratory Research, 2024 - Springer
… We then discuss the interactions among macrophages, cytokines, and vascular adventitial …
and oestrogen receptors are regarded as promising therapeutic targets in PH [50]. Additionally…
and oestrogen receptors are regarded as promising therapeutic targets in PH [50]. Additionally…
[PDF][PDF] IL-1R2: a novel approach for gene therapy in atherosclerosis
F Ahmadi, A Esmaeilzadeh - Hypothesis J, 2016 - researchgate.net
… Cytokines in atherosclerosis: Key players in all stages of disease and promising
therapeutic targets. Cytokine Growth Factor Rev 2015: S1359-6101(15):32-5. …
therapeutic targets. Cytokine Growth Factor Rev 2015: S1359-6101(15):32-5. …
[HTML][HTML] Advances in pathophysiology of calcific aortic valve disease propose novel molecular therapeutic targets
A Hulin, A Hego, P Lancellotti, C Oury - Frontiers in cardiovascular …, 2018 - frontiersin.org
… exploitation as promising therapeutic targets to treat CAVD and reduce valve replacement. …
pro-inflammatory cytokines among which IL-6 and TNF-α. Proinflammatory cytokines impairs …
pro-inflammatory cytokines among which IL-6 and TNF-α. Proinflammatory cytokines impairs …