Can adiponectin help us to target diastolic dysfunction?
C Francisco, JS Neves, I Falcão-Pires… - … drugs and therapy, 2016 - Springer
… Atherosclerosis is characterized by chronic systemic inflammation. The first change
preceding the formation of lesions of atherosclerosis is endothelial injury, which is mediated by …
preceding the formation of lesions of atherosclerosis is endothelial injury, which is mediated by …
Intercellular communication lessons in heart failure
C Bang, C Antoniades… - European journal of …, 2015 - Wiley Online Library
… communication networks and respective underlying mechanisms which could be involved
in cardiovascular disease conditions and further emphasize promising therapeutic targets for …
in cardiovascular disease conditions and further emphasize promising therapeutic targets for …
Liver X receptors, atherosclerosis and inflammation
DR Michael, TG Ashlin, ML Buckley… - Current atherosclerosis …, 2012 - Springer
… atherosclerosis in mouse model systems (see below) and therefore represent promising
therapeutic targets … by factors such as thyroid hormone and certain cytokines [9–11]. Alternative …
therapeutic targets … by factors such as thyroid hormone and certain cytokines [9–11]. Alternative …
Tumor-Associated Macrophages: Therapeutic Targets of Cancer
… The chapter highlighted TAMs as promising therapeutic targets of cancer, which might be …
H 1 cytokines such as INF-γ, M2 type macrophages are induced by the T H 2 cytokines such as …
H 1 cytokines such as INF-γ, M2 type macrophages are induced by the T H 2 cytokines such as …
[HTML][HTML] Diabetic nephropathy: novel molecular mechanisms and therapeutic targets
C Zoja, C Xinaris, D Macconi - Frontiers in Pharmacology, 2020 - frontiersin.org
… Despite these difficulties, experimental models of diabetes have revealed promising therapeutic
targets by identifying pathways that modulate key functions of podocytes and glomerular …
targets by identifying pathways that modulate key functions of podocytes and glomerular …
[HTML][HTML] Zinc-dependent histone deacetylases: Potential therapeutic targets for arterial hypertension
HJ Kee, I Kim, MH Jeong - Biochemical Pharmacology, 2022 - Elsevier
… Although the phenotypic analysis of hypertension in isoform HDAC deletion mice is required,
few HDACs (HDAC3, HDAC4, and HDAC8) are promising therapeutic targets for treating …
few HDACs (HDAC3, HDAC4, and HDAC8) are promising therapeutic targets for treating …
Mechanisms by which diabetes increases cardiovascular disease
… Increasing prevalence of diabetes and diabetic atherosclerosis … which may represent
promising therapeutic targets. … syndrome seem to represent promising therapeutic targets. This is …
promising therapeutic targets. … syndrome seem to represent promising therapeutic targets. This is …
Therapeutic targets in alcohol-associated liver disease: progress and challenges
AD Adekunle, A Adejumo… - Therapeutic Advances in …, 2023 - journals.sagepub.com
… Although there are promising therapeutic targets on the horizon, none of the newer targets is
… proinflammatory cytokines including tumor necrosis factor alpha (TNFα), interleukin 1 (IL1). …
… proinflammatory cytokines including tumor necrosis factor alpha (TNFα), interleukin 1 (IL1). …
Pathogenic mechanisms following ischemic stroke
… ischemic stroke and reveal the intertwined pathways that are promising therapeutic targets.
… of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. These cytokines can potentiate …
… of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. These cytokines can potentiate …
[HTML][HTML] The NLRP3 Inflammasome as a Pathogenic Player Showing Therapeutic Potential in Rheumatoid Arthritis and Its Comorbidities: A Narrative Review
… inflammasome signaling pathway represent promising therapeutic targets, and ongoing …
pro-inflammatory cytokines. MCC950 could reduce macrophage infiltration and atherosclerotic …
pro-inflammatory cytokines. MCC950 could reduce macrophage infiltration and atherosclerotic …