MicroRNAs and lipid metabolism

B Aryal, AK Singh, N Rotllan, N Price… - Current opinion in …, 2017 - journals.lww.com
… MicroRNAs have emerged as critical regulators of cholesterol metabolism and promising
therapeutic targets for treating cardiometabolic disorders including atherosclerosis. Here, we …

[引用][C] Cytkines in atherosclerosis: molecular mechanisms underlying their actions and promising therapeutic targets

D Ramji, T Davies, H Gallagher, J Moss… - Journal of Clinical …, 2016 - orca.cardiff.ac.uk
… : molecular mechanisms underlying their actions and promising therapeutic targets [Abstract] …
: molecular mechanisms underlying their actions and promising therapeutic targets [Abstract…

[HTML][HTML] Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and …

M Autiero, A Luttun, M Tjwa, P Carmeliet - Journal of Thrombosis and …, 2003 - Elsevier
… Thus, these preclinical studies show proof-of-principle that PlGF and VEGFR-1 are promising
therapeutic targets to treat angiogenesis and inflammation related disorders. Clinical trials …

Molecular mechanisms underlying the inhibition of IFN‐γ‐induced, STAT1‐mediated gene transcription in human macrophages by simvastatin and agonists of PPARs …

N Li, RC Salter, DP Ramji - Journal of cellular biochemistry, 2011 - Wiley Online Library
… transcription factors that are emerging as promising therapeutic targets for limiting
atherosclerosis, an inflammatory disorder orchestrated by cytokines. The potent anti-atherogenic …

Tissue-type plasminogen activator as a therapeutic target in stroke

I Gravanis, SE Tsirka - Expert opinion on therapeutic targets, 2008 - Taylor & Francis
… endogenous tPA have both turned into promising therapeutic targets for the stroke patient. …
of pharmacotherapy can all help prevent atherosclerosis, the major culprit behind ischemic …

Endothelial dysfunction and cardiometabolic diseases: Role of long non-coding RNAs

HJ Sun, B Hou, X Wang, XX Zhu, KX Li, LY Qiu - Life sciences, 2016 - Elsevier
… LncRNAs may become promising therapeutic targets in endothelial dysfunction-related …
endothelial cells via inhibition of proinflammatory cytokines, platelet aggregation or cell adhesion …

[HTML][HTML] Macrophage polarization states in atherosclerosis

J Wu, S He, Z Song, S Chen, X Lin, H Sun… - Frontiers in …, 2023 - frontiersin.org
… -activated receptor (PPAR)-γ, and can reduce cytokine-induced systemic inflammation to
prevent the progression of atherosclerotic plaques (65). Similarly, Oleoylethanolamide is an …

[HTML][HTML] Systematic review of the role of angiopoietin-1 and angiopoietin-2 in Plasmodium species infections: biomarkers or therapeutic targets?

GM De Jong, JJ Slager, A Verbon, JJ van Hellemond… - Malaria Journal, 2016 - Springer
… treatment effectiveness and are promising therapeutic targets as part of multi-targeted
therapy. … vivax leads to disproportional organ-specific parasitaemia and what role the cytokine

Monocyte subpopulations and cardiovascular risk in chronic kidney disease

GH Heine, A Ortiz, ZA Massy, B Lindholm… - Nature reviews …, 2012 - nature.com
… activation, are promising therapeutic targets for tackling … the increased production of cytokines
by monocytes could be … clearance of cytokines might contribute to elevated cytokine levels …

Adiponectin and adipocyte fatty acid binding protein in the pathogenesis of cardiovascular disease

A Xu, PM Vanhoutte - American Journal of Physiology …, 2012 - journals.physiology.org
… for cardiovascular disease and even promising therapeutic targets for its treatment. … The
secretion of MCP-1, a key pathological cytokine in vascular inflammation and atherosclerosis, …