[HTML][HTML] β-Caryophyllene, a natural dietary CB2 receptor selective cannabinoid can be a candidate to target the trinity of infection, immunity, and inflammation in Covid …

NK Jha, C Sharma, HM Hashiesh… - Frontiers in …, 2021 - frontiersin.org
… One of the most promising therapeutic targets for the modulation of immune-inflammatory …
This causes the onset of a “cytokine storm” or “cytokine release syndrome”, which mainly …

[HTML][HTML] FGF23 and phosphate–cardiovascular toxins in CKD

I Vogt, D Haffner, M Leifheit-Nestler - Toxins, 2019 - mdpi.com
… Therefore, FGF23 and phosphate are considered promising therapeutic targets to improve
the cardiovascular outcome in CKD patients. Previous therapeutic strategies are based on …

[HTML][HTML] Inflammasomes in the pathophysiology of aortic disease

M Wortmann, AS Peters, P Erhart, D Körfer, D Böckler… - Cells, 2021 - mdpi.com
… We will also identify research gaps and suggest promising therapeutic targets, which may …
, cytokines, and autoimmunity within the aortic wall, predominantly focusing on atherosclerosis

[HTML][HTML] The role of micrornas in diabetic complications—special emphasis on wound healing

J Moura, E Børsheim, E Carvalho - Genes, 2014 - mdpi.com
… These molecules are promising therapeutic targets and demonstrate great potential as
diagnostic biomarkers for disease. This review aims to describe the most recent findings …

[HTML][HTML] New insights into intestinal macrophages in necrotizing enterocolitis: the multi-functional role and promising therapeutic application

J Wei, Z Meng, Z Li, D Dang, H Wu - Frontiers in Immunology, 2023 - frontiersin.org
… (2) The pro-inflammatory cytokines and regenerative signals released by IMφs affects the …
5p, which inhibit the activation NLRP3, are promising therapeutic targets in NEC (112, 113). …

Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis

B Zhou, A Margariti, L Zeng, Q Xu - Cardiovascular research, 2011 - academic.oup.com
… cell differentiation and atherosclerosis is provided. Overall, HDACs appear to be promising
therapeutic targets for the treatment of arteriosclerosis and other cardiovascular diseases. …

[HTML][HTML] Promising Therapeutic Treatments for Cardiac Fibrosis: Herbal Plants and Their Extracts

X Yu - Cardiology and Therapy, 2023 - Springer
… Neurohormones and cytokines play indispensable roles in cardiac fibrosis. Many signaling
pathways participate … TSPs are promising therapeutic targets for treating cardiac fibrosis [77]. …

Interleukins (ILs), a fascinating family of cytokines. Part II: ILs from IL-20 to IL-38.

P Fietta, E Costa, G Delsante - THEORETICAL BIOLOGY, 2015 - torrossa.com
… Therefore, they have increasingly attracted great interest as effective or promising therapeutic
targets. The biology and functions of the hitherto identified human ILs are reviewed and …

Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

JI Jun, LF Lau - Nature reviews Drug discovery, 2011 - nature.com
… molecules such as growth factors, cytokines, chemokines and extracellular enzymes, or … ,
suggesting that CCN proteins are promising therapeutic targets in these pathologies. Clinical …

Regulatory non‐coding RNA s in acute myocardial infarction

Y Guo, F Luo, Q Liu, D Xu - Journal of cellular and molecular …, 2017 - Wiley Online Library
… Recently, some lncRNAs and circRNAs were identified as vital biomarkers and promising
therapeutic targets in AMI 39, 40 (Table 1 and Fig. 1B). The circulating lncRNA urothelial …