[HTML][HTML] Cellular and molecular therapeutic targets in inflammatory bowel disease—focusing on intestinal barrier function

I Schoultz, ÅV Keita - Cells, 2019 - mdpi.com
… , with elevated secretion of pro-inflammatory cytokines that can affect the epithelium and …
links to ulcerative colitis that are potential therapeutic targets, and for example, neutrophil …

Cytokines as Potential Therapeutic Targets and their Role in the Diagnosis and Prediction of Cancers

I Uchendu, A Zhilenkova, Y Pirogova… - Current …, 2023 - ingentaconnect.com
cytokines are promising markers of tumor stage, prognosis, and responsiveness to therapy.
In fact, several cytokines … It has actually been proposed that the study of circulatory cytokines

Phosphorylation events during viral infections provide potential therapeutic targets

JA Keating, R Striker - Reviews in medical virology, 2012 - Wiley Online Library
For many medically relevant viruses, there is now considerable evidence that both viral and
cellular kinases play important roles in viral infection. Ultimately, these kinases, and the …

[HTML][HTML] High mobility group proteins in sepsis

G Liang, Z He - Frontiers in Immunology, 2022 - frontiersin.org
… A growing number of studies have demonstrated HMGs are not only cytokines which can
mediate inflammation, but also potential therapeutic targets in sepsis. To reduce sepsis-related …

[HTML][HTML] Immunological mechanisms and therapeutic targets of fatty liver diseases

H Wang, W Mehal, LE Nagy, Y Rotman - Cellular & Molecular …, 2021 - nature.com
… signaling and subsequently produced inflammatory cytokines such as tumor necrosis factor
… hits have been investigated as potential therapeutic targets. Inflammation is one of the main …

[HTML][HTML] miRNAs, from evolutionary junk to possible prognostic markers and therapeutic targets in COVID-19

B Bautista-Becerril, G Pérez-Dimas… - Viruses, 2021 - mdpi.com
… due to low oxygen supplies or increased cytokines, as observed in sepsis. Approximately
19% of … and viral infection, miRNAs appear to be potential therapeutic targets in viral diseases. …

Chemokines in myocardial failure–pathogenic importance and potential therapeutic targets

P Aukrust, JK Damås, L Gullestad… - Clinical & Experimental …, 2001 - academic.oup.com
… In particular, although several cytokines may prime phagocytes for enhanced ROS … Indeed,
we have recently shown that MCP-1 stimulates the release of other inflammatory cytokines (ie …

The role of inflammasomes in COVID-19: potential therapeutic targets

C Sun, H Zhao, Y Han, Y Wang… - … of Interferon & Cytokine …, 2022 - liebertpub.com
… of inflammasomes following COVID-19 infection and provides recent evidence on the … causes
excessive production of proinflammatory cytokines (cytokine storm), increased risk of acute …

[HTML][HTML] Elucidating common pathogenic transcriptional networks in infective endocarditis and sepsis: integrated insights from biomarker discovery and single-cell …

C Yi, H Zhang, J Yang, D Chen, S Jiang - Frontiers in Immunology, 2024 - frontiersin.org
… diagnostic genes and inflammatory cytokines in sepsis clusters sample(G-sepsis cluster1,H- …
(IE) and sepsis, uncovering common biomarkers and potential therapeutic targets. Through …

[HTML][HTML] Potential Therapeutic Targets for Combination Antibody Therapy against Pseudomonas aeruginosa Infections

LL Proctor, WL Ward, CS Roggy, AG Koontz, KM Clark… - Antibiotics, 2021 - mdpi.com
… This manuscript details the development of potential therapeutic targets for polyclonal
antibody therapies to combat the emergence of multidrug-resistant P. aeruginosa infections. In …