Pharmacological manipulation of granulocyte apoptosis: potential therapeutic targets
C Ward, I Dransfield, ER Chilvers, C Haslett… - Trends in …, 1999 - cell.com
Resolution of inflammation involves the clearance of excess or effete inflammatory cells by
a process of physiological programmed cell death (apoptosis) and the subsequent …
a process of physiological programmed cell death (apoptosis) and the subsequent …
Immunological mechanisms and therapeutic targets of fatty liver diseases
… signaling and subsequently produced inflammatory cytokines such as tumor necrosis factor
… hits have been investigated as potential therapeutic targets. Inflammation is one of the main …
… hits have been investigated as potential therapeutic targets. Inflammation is one of the main …
New therapeutic targets in alcoholic hepatitis
D Arsene, O Farooq, R Bataller - Hepatology international, 2016 - Springer
… through secretion of anti-inflammatory cytokines, including IL-6 and IL-10. Through
activation of STAT3, these cytokines curb inflammation and slow progression of liver injury [66–68]. …
activation of STAT3, these cytokines curb inflammation and slow progression of liver injury [66–68]. …
Hypoxia, HIF-1α, and COVID-19: from pathogenic factors to potential therapeutic targets
ZO Serebrovska, EY Chong, TV Serebrovska… - Acta Pharmacologica …, 2020 - nature.com
… as “cytokine storm”, … cytokines leading to cytokine storm include tumor necrosis factor α
(TNFα), interleukin 6 and 1β (IL-6 and IL-1β) [7]. The high volume of swiftly increasing cytokines …
(TNFα), interleukin 6 and 1β (IL-6 and IL-1β) [7]. The high volume of swiftly increasing cytokines …
[HTML][HTML] Crosstalk between hypoxic cellular micro-environment and the immune system: a potential therapeutic target for infectious diseases
… infection and inflammatory process, and the involvement of other co-stimulatory factors, like
pro-inflammatory cytokines… of pathogenesis and identifying potential therapeutic targets. This …
pro-inflammatory cytokines… of pathogenesis and identifying potential therapeutic targets. This …
Cytokine pathways and investigational target therapies in hidradenitis suppurativa
E Del Duca, P Morelli, L Bennardo… - International journal of …, 2020 - mdpi.com
… We will discuss the pathogenetic role of various cytokines in HS and potential therapeutic
targets for this debilitating disease. Results: The pathophysiology underlying this complex …
targets for this debilitating disease. Results: The pathophysiology underlying this complex …
Sepsis-Associated Acute Kidney Injury: Where Are We Now?
D Kounatidis, NG Vallianou, S Psallida… - Medicina, 2024 - mdpi.com
… also serve as potential therapeutic targets. The combination of … the development of potential
therapeutic targets that could … avoidance of the cytokine storm observed in sepsis. Therefore, …
therapeutic targets that could … avoidance of the cytokine storm observed in sepsis. Therefore, …
Exploring immune checkpoints as potential therapeutic targets in atherosclerosis
PJH Kusters, E Lutgens… - Cardiovascular research, 2018 - academic.oup.com
… Interactions between different immune cells result in the secretion of inflammatory mediators,
such as cytokines and chemokines, and fuel atherogenesis. Immune checkpoint proteins …
such as cytokines and chemokines, and fuel atherogenesis. Immune checkpoint proteins …
Coagulation and fibrinolysis in human acute lung injury—new therapeutic targets?
LB Ware, JA Bastarache, L Wang - The Keio journal of medicine, 2005 - jstage.jst.go.jp
… This review summarizes our current understanding of coagulation and fibrinolysis in
human ALI/ARDS with an emphasis on pathways that could be potential therapeutic targets …
human ALI/ARDS with an emphasis on pathways that could be potential therapeutic targets …
ADAM-family metalloproteinases in lung inflammation: potential therapeutic targets
D Dreymueller, S Uhlig… - American Journal of …, 2015 - journals.physiology.org
… Shedding significantly modulates the activity of growth factors, adhesion molecules,
receptors, and cytokines by the release of soluble ectodomains acting as either antagonists or …
receptors, and cytokines by the release of soluble ectodomains acting as either antagonists or …