… of sepsis-induced organ failure unveils potential therapeutic targets for sepsis treatment. …
excessive production of cytokines, which leads to a stage known as a cytokine storm. This …

… through secretion of anti-inflammatory cytokines, including IL-6 and IL-10. Through
activation of STAT3, these cytokines curb inflammation and slow progression of liver injury [66–68]. …

… The binding of Aβ to TLRs activates microglia and triggers the production of proinflammatory
cytokines. Aβ-bound TLR initiates a number of signaling cascades through myeloid …

… minimize the deleterious consequences of SARS-CoV-2 infection, such as by controlling or
inhibiting the generation of cytokines and chemokines. The degradation of viral RNA by the …

… Shedding significantly modulates the activity of growth factors, adhesion molecules,
receptors, and cytokines by the release of soluble ectodomains acting as either antagonists or …

… the expression of various inflammatory cytokines, type I interferons, … the expression of many
cytokine and chemokine genes … interrogated as potential therapeutic targets include TLR7/9, …

… We review potential therapeutic targets to shift microglial polarization. Finally, we review the
… cytokines stimulate other immune cells, but also stimulate surrounding microglia. Cytokines …

… Relative deficiency of Th1 cytokines might lead to delayed clearance of bacterial antigens …
with AS who showed impaired production of Th1 cytokines improved their cytokine profile [33], …

… cystic fibrosis, sepsis, and ulcerative colitis has increasingly been linked to runaway cytokine-…
potential therapeutic targets for many diseases that have a strong inflammatory component. …

… syndrome coronavirus 2 (SARS-CoV-2), which are essential for its functionality, survival,
and pathogenesis have been identified and are considered as potential therapeutic targets. …