[HTML][HTML] Neuroinflammation after intracerebral hemorrhage and potential therapeutic targets

C Tschoe, CD Bushnell, PW Duncan… - Journal of …, 2020 - ncbi.nlm.nih.gov
… Based on a growing body of evidence, activated microglia appear to be the main source of
cytokines… In order to identify potential therapeutic targets and effectively treat the inflammatory …

[HTML][HTML] Promising therapeutic targets for treatment of rheumatoid arthritis

J Huang, X Fu, X Chen, Z Li, Y Huang… - Frontiers in …, 2021 - frontiersin.org
… in RA could facilitate discovery of potential therapeutic targets and approaches. In this review,
… literature published between 2005 and 2021 using keywords cytokines,” “chemokines,” “…

[HTML][HTML] Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
… Intriguingly, systemic investigation of SARS-CoV-2 infection identified signaling pathways
and key genes/proteins associated with COVID-19’s main hallmarks, eg, cytokine storm, …

Interleukin-18: a pro-inflammatory cytokine that plays an important role in acute pancreatitis

BS Yuan, RM Zhu, M Braddock, XH Zhang… - Expert opinion on …, 2007 - Taylor & Francis
… evidence suggests that cytokines play a key role in the pathogenesis of local and systemic
complications of acute pancreatitis. IL-18 is a pro-inflammatory cytokine that plays a key role …

Identifying and validating potential therapeutic targets for septic heart failure and the cardioprotective effects of lycorine

Q Liu, A Zhao, X Wu, X Zhang, X Li, W Yang, W Lei… - Phytomedicine, 2024 - Elsevier
… key sepsis target and explore the possible target for LYC effect. These findings … potential
therapeutic targets and adjuvant treatment strategies for the management of sepsis and septic

Therapeutic targets for cholestatic liver injury

BL Woolbright, H Jaeschke - Expert opinion on therapeutic targets, 2016 - Taylor & Francis
potential therapeutic targets related to bile acid signaling as it is currently understood. …
cytokines in response to bile acid exposure, linking the in vitro upregulation of cytokines and pro-…

[HTML][HTML] Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets

DP Misra, V Agarwal, AY Gasparyan, O Zimba - Clinical rheumatology, 2020 - Springer
… Severe disease in a subset of patients may be driven by cytokine storm, possibly due to …
Cytokine storm and secondary HLH might require heightened immunosuppressive regimens…

Are Th17 cells and their cytokines a therapeutic target in Guillain–Barré syndrome?

X Wu, J Wang, K Liu, J Zhu… - Expert Opinion on …, 2016 - Taylor & Francis
… roles of Th17 cells and their cytokines in GBS/EAN, which is important for evaluating whether
Th17 cells and cytokines could serve as potential therapeutic targets in GBS. In addition, …

Membrane-bound complement regulatory proteins as biomarkers and potential therapeutic targets for SLE

N Das, B Biswas, R Khera - Complement Therapeutics, 2013 - Springer
For the last two decades, there had been remarkable advancement in understanding the
role of complement regulatory proteins in autoimmune disorders and importance of …

[HTML][HTML] Type I interferon: potential therapeutic target for psoriasis?

Y Yao, L Richman, C Morehouse, M de los Reyes… - PloS one, 2008 - journals.plos.org
… in lesional skin underscore the importance of this cytokine in psoriasis; these data describe
a … skin suggest that type I IFNs may be potential therapeutic targets in psoriasis treatment. …