[HTML][HTML] Autophagy: a potential therapeutic target for reversing sepsis-induced immunosuppression
C Ren, H Zhang, T Wu, Y Yao - Frontiers in Immunology, 2017 - frontiersin.org
… pathogens and releasing pro-inflammatory cytokines (58, 59). … potential therapeutic targets
that are concerned with autophagy for reversing immunosuppression compromised by sepsis…
that are concerned with autophagy for reversing immunosuppression compromised by sepsis…
Kinases as potential therapeutic targets for anti-coronaviral therapy
T Pillaiyar, S Laufer - Journal of Medicinal Chemistry, 2021 - ACS Publications
… the viral infection cycle (entry, replication, assembly, and egress), and several of them are
involved in the virus-induced hyperinflammatory response that leads to cytokine storm, acute …
involved in the virus-induced hyperinflammatory response that leads to cytokine storm, acute …
Mitochondrial quality control mechanisms as potential therapeutic targets in sepsis-induced multiple organ failure
Y Wu, YM Yao, ZQ Lu - Journal of Molecular Medicine, 2019 - Springer
… Sepsis is a dysregulated response to severe infection … of sepsis and is associated with poor
outcome of septic patients. … dysfunction are reported in sepsis. Mitochondrial dysfunction with …
outcome of septic patients. … dysfunction are reported in sepsis. Mitochondrial dysfunction with …
Cytokines in Sjögren's syndrome: potential therapeutic targets
N Roescher, PP Tak, GG Illei - Annals of the rheumatic diseases, 2010 - ard.bmj.com
… of cytokines on the most important pathological processes (white ovals) are shown by blue
arrows. The effect of some cytokines … Cytokines in the red framed boxes depict cytokines that …
arrows. The effect of some cytokines … Cytokines in the red framed boxes depict cytokines that …
Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets
… This review will highlight some of the key cytokines and their roles in the … cytokines as well
as their receptors. A comprehensive coverage of the roles of the full spectrum of cytokines in …
as their receptors. A comprehensive coverage of the roles of the full spectrum of cytokines in …
Interleukin 28 is a potential therapeutic target for sepsis
Q Luo, Y Liu, S Liu, Y Yin, B Xu, J Cao - Clinical Immunology, 2019 - Elsevier
… CLP-induced sepsis mortality, while IL-28 administration in sepsis increased mortality. This
study identifies cytokine IL-28 as a new immunotherapeutic agent for the treatment of sepsis. …
study identifies cytokine IL-28 as a new immunotherapeutic agent for the treatment of sepsis. …
Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation
A Paniri, H Akhavan-Niaki - Life Sciences, 2020 - Elsevier
… the major cause of inflammatory cytokine storm, and thereby … are implicated in inflammatory
cytokine storm and inflammatory … drugs to target inflammatory cytokines especially IL-6 and …
cytokine storm and inflammatory … drugs to target inflammatory cytokines especially IL-6 and …
High-mobility group box-1 isoforms as potential therapeutic targets in sepsis
W Parrish, L Ulloa - Target Discovery and Validation Reviews and …, 2007 - Springer
… extracellular milieu where it functions as a proinflammatory cytokine. Indeed, HMGB1
represents a novel family of inflammatory cytokines composed of intracellular proteins that can be …
represents a novel family of inflammatory cytokines composed of intracellular proteins that can be …
[HTML][HTML] Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets
… Severe disease in a subset of patients may be driven by cytokine storm, possibly due to …
Cytokine storm and secondary HLH might require heightened immunosuppressive regimens…
Cytokine storm and secondary HLH might require heightened immunosuppressive regimens…
Essential functional molecules associated with SARS-CoV-2 infection: Potential therapeutic targets for COVID-19
… syndrome coronavirus 2 (SARS-CoV-2), which are essential for its functionality, survival,
and pathogenesis have been identified and are considered as potential therapeutic targets. …
and pathogenesis have been identified and are considered as potential therapeutic targets. …