Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways
… Impeding the risk associated with the imbalance in the inflammatory response requires
precise identification of potential therapeutic targets involved in provoking the inflammation. Toll-…
precise identification of potential therapeutic targets involved in provoking the inflammation. Toll-…
Cytokines in common variable immunodeficiency as signs of immune dysregulation and potential therapeutic targets–a review of the current knowledge
FN Varzaneh, B Keller, S Unger… - Journal of clinical …, 2014 - Springer
… Common cytokine profiles might reflect … cytokines vary significantly between the studies.
While some studies measured the serum level of cytokines, others reported in vitro cytokine …
While some studies measured the serum level of cytokines, others reported in vitro cytokine …
Pro-inflammatory cytokines: new potential therapeutic targets for obesity-related bone disorders
T Wang, C He, X Yu - Current Drug Targets, 2017 - ingentaconnect.com
… cytokines [9, 10]. White fat may attribute to osteoporosis by disrupting bone metabolism by
releasing inflammatory cytokines … They are the major proinflammatory cytokines secreted from …
releasing inflammatory cytokines … They are the major proinflammatory cytokines secreted from …
[HTML][HTML] Coronavirus infection-associated cell death signaling and potential therapeutic targets
R Yapasert, P Khaw-On, R Banjerdpongchai - Molecules, 2021 - mdpi.com
… SARS-CoV-2 infection, sepsis, HLH, and cytokine shock. Inhibiting the cytokine-mediated …
together to cause the cytokine storm and cell death linked to COVID-19 and sepsis. It was …
together to cause the cytokine storm and cell death linked to COVID-19 and sepsis. It was …
COVID-19 associated complications and potential therapeutic targets
JD Monpara, SJ Sodha, PK Gupta - European Journal of Pharmacology, 2020 - Elsevier
… The underlying mechanism responsible for hypercoagulation is associated with inflammatory
state and cytokine storm resulting from host defense system. The objective of this review is …
state and cytokine storm resulting from host defense system. The objective of this review is …
The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2
… Based on the current status, the elderly population and people with prior co-morbidities
are highly susceptible to serious health effects including cytokine up-regulation and acute …
are highly susceptible to serious health effects including cytokine up-regulation and acute …
[HTML][HTML] Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2 infection
has become a global pandemic due to the high viral transmissibility and pathogenesis, …
has become a global pandemic due to the high viral transmissibility and pathogenesis, …
[HTML][HTML] Eicosanoids and respiratory viral infection: coordinators of inflammation and potential therapeutic targets
MK McCarthy, JB Weinberg - Mediators of inflammation, 2012 - hindawi.com
… In contrast, influenza infection of mice genetically deficient in COX-2 resulted in reduced
mortality, inflammation, and cytokine responses compared to infection of wild-type control [99]. …
mortality, inflammation, and cytokine responses compared to infection of wild-type control [99]. …
The role of inflammasomes in COVID-19: potential therapeutic targets
C Sun, H Zhao, Y Han, Y Wang… - … of Interferon & Cytokine …, 2022 - liebertpub.com
… of inflammasomes following COVID-19 infection and provides recent evidence on the … causes
excessive production of proinflammatory cytokines (cytokine storm), increased risk of acute …
excessive production of proinflammatory cytokines (cytokine storm), increased risk of acute …
[HTML][HTML] Toll-like receptors as potential therapeutic targets for multiple diseases
C Zuany-Amorim, J Hastewell, C Walker - Nature Reviews Drug …, 2002 - nature.com
… of the pathogenesis of sepsis indicates that bacteria and bacterial products activate an
uncontrolled network of host-derived mediators, such as pro-inflammatory cytokines, that can lead …
uncontrolled network of host-derived mediators, such as pro-inflammatory cytokines, that can lead …