Mitochondrial quality control mechanisms as potential therapeutic targets in sepsis-induced multiple organ failure
Y Wu, YM Yao, ZQ Lu - Journal of Molecular Medicine, 2019 - Springer
… Sepsis is a dysregulated response to severe infection … of sepsis and is associated with poor
outcome of septic patients. … dysfunction are reported in sepsis. Mitochondrial dysfunction with …
outcome of septic patients. … dysfunction are reported in sepsis. Mitochondrial dysfunction with …
Arterial hypertension and interleukins: potential therapeutic target or future diagnostic marker?
… These cytokines (IL-6) trigger hypertensive responses to angiotensin II infusion even in
normotensive individuals, which presents new potential therapeutic targets [6–8]. …
normotensive individuals, which presents new potential therapeutic targets [6–8]. …
Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets
… This review will highlight some of the key cytokines and their roles in the … cytokines as well
as their receptors. A comprehensive coverage of the roles of the full spectrum of cytokines in …
as their receptors. A comprehensive coverage of the roles of the full spectrum of cytokines in …
The role of ubiquitination in microbial infection induced endothelial dysfunction: potential therapeutic targets for sepsis
J Wang, Y He, D Zhou - Expert Opinion on Therapeutic Targets, 2023 - Taylor & Francis
… many mechanisms of ubiquitination-mediated regulation with a focus on those that modulate
endothelial function to provide potential therapeutic targets for the management of sepsis. …
endothelial function to provide potential therapeutic targets for the management of sepsis. …
Inflammatory mechanisms as potential therapeutic targets in stroke
MA Mir, RS Albaradie - Advances in Neuroimmune Biology, 2014 - content.iospress.com
… of biochemical events are potential therapeutic targets for the … infection cytokines are
produced outside and within the brain and mediate aspects of sickness behavior [36]. Infection after …
produced outside and within the brain and mediate aspects of sickness behavior [36]. Infection after …
c-Jun N-terminal kinases as potential therapeutic targets
B Salh - Expert Opinion on Therapeutic Targets, 2007 - Taylor & Francis
… B Streptococcal (GBS) infection of newborn infants, who do … cytokine gene expression using
peritoneal macrophages and Raw 264.7 cells, as well as survival in a GBS neonatal sepsis …
peritoneal macrophages and Raw 264.7 cells, as well as survival in a GBS neonatal sepsis …
Toll-like receptors as potential therapeutic targets in cardiac dysfunction
U Hofmann, G Ertl, S Frantz - Expert opinion on therapeutic targets, 2011 - Taylor & Francis
… They showed that cardiac myosin activates TLR2 and TLR8 in human monocytes and
induces release of proinflammatory cytokines. Cardiac myosin may function as a TLR ligand by …
induces release of proinflammatory cytokines. Cardiac myosin may function as a TLR ligand by …
Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation
A Paniri, H Akhavan-Niaki - Life Sciences, 2020 - Elsevier
… the major cause of inflammatory cytokine storm, and thereby … are implicated in inflammatory
cytokine storm and inflammatory … drugs to target inflammatory cytokines especially IL-6 and …
cytokine storm and inflammatory … drugs to target inflammatory cytokines especially IL-6 and …
A two-decade journey in identifying high mobility group box 1 (HMGB1) and procathepsin L (Pcts-L) as potential therapeutic targets for sepsis
J Li, CS Zhu, L He, X Qiang, W Chen… - Expert Opinion on …, 2023 - Taylor & Francis
… support HMGB1 and pCTS-L as potential therapeutic targets for improving survival in sepsis.
… , and distinguished itself from other early proinflammatory cytokines [Citation70]. In animal …
… , and distinguished itself from other early proinflammatory cytokines [Citation70]. In animal …
[PDF][PDF] Pro-Inflammatory Cytokines as Potential Early Biomarkers and Therapeutic Targets to Combat Ischemic Stroke
M Agrawal - academia.edu
… during ischemic stroke that would make the inflammatory cytokines as not only possible
biomarkers but potential therapeutic targets. The knowledge of modulation of the possible …
biomarkers but potential therapeutic targets. The knowledge of modulation of the possible …