Potential therapeutic targets for COVID-19 complicated with pulmonary hypertension: a bioinformatics and early validation study

Q Hou, J Jiang, K Na, X Zhang, D Liu, Q Jing, C Yan… - Scientific Reports, 2024 - nature.com
… simplex virus 1 infection, viral protein interaction with cytokine and cytokine receptor, malaria,
Infection with SARS-CoV-2 may cause a cytokine storm leading to systemic inflammation …

Current status of potential therapeutic candidates for the COVID-19 crisis

J Zhang, B Xie, K Hashimoto - Brain, behavior, and immunity, 2020 - Elsevier
infection. Furthermore, intensive research and clinical trials are underway to assess the
efficacy of existing drugs and identify potential therapeutic targets … -2 infection-induced cytokine

Traumatic injury to the immature brain: inflammation, oxidative injury, and iron-mediated damage as potential therapeutic targets

MB Potts, SE Koh, WD Whetstone, BA Walker… - NeuroRx, 2006 - Elsevier
… with septic shock, 37 demonstrating the magnitude of inflammation in the injured immature
brain. Although these cytokines … They comprise a family of structurally related cytokines that …

Pulmonary inflammatory response in lethal COVID-19 reveals potential therapeutic targets and drugs in phases III/IV clinical trials

A López-Cortés, S Guerrero, E Ortiz-Prado… - Frontiers in …, 2022 - frontiersin.org
… to reveal potential therapeutic targets and drugs in advanced-stage COVID-19 clinical trials.
… -omics analysis to identify potential therapeutic targets and drugs to treat severe COVID-19. …

Signaling pathways of oxidative stress response: The potential therapeutic targets in gastric cancer

Y Liu, Y Shi, R Han, C Liu, X Qin, P Li, R Gu - Frontiers in immunology, 2023 - frontiersin.org
cytokine IL-8 production and minimize the infection via the Nrf2/HO-1 pathway in the AGS
cells (161). It is reported that omega-3 fatty acids inhibit the oxidation of polyunsaturated long-…

[HTML][HTML] Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma …

YH Wu, IJ Yeh, NN Phan, MC Yen, JH Hung… - … and Infection, 2021 - Elsevier
… TNFAIP3 responded to duck Tembusu viral infection, 44 LEAP-2 plays a crucial role in
immune activation as well as cytokine production for human immunodeficiency virus (HIV)/…

G-CSF and G-CSFR modulate CD4 and CD8 T cell responses to promote colon tumor growth and are potential therapeutic targets

I Karagiannidis, SJ Jerman, D Jacenik… - Frontiers in …, 2020 - frontiersin.org
Cytokines are known to shape the tumor microenvironment … (G-CSF) as one such cytokine,
showing that G-CSF is linked … Flow cytometry, Real Time PCR and Multiplex cytokine array …

Hepatic macrophages in liver fibrosis: pathogenesis and potential therapeutic targets

H Li, H You, X Fan, J Jia - BMJ open gastroenterology, 2016 - bmjopengastro.bmj.com
… cells, and the secretion of proinflammatory cytokines and chemokines in the early stages,
these … in liver fibrosis and the potential therapeutic targets that modulate hepatic macrophages. …

Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
Microbe–host communication is essential to maintain vital functions of a healthy host, and
its disruption has been associated with several diseases, including Crohn’s disease and …

Brain-derived neurotrophic factor (BDNF)-TrkB signaling in inflammation-related depression and potential therapeutic targets

J Zhang, W Yao, K Hashimoto - Current neuropharmacology, 2016 - ingentaconnect.com
… of pro-inflammatory cytokines, such as IL 1β and TNF-α. These cytokines are capable of
inducing … Proinflammatory cytokines were activated in the brain in response to peripheral …