The role of cytokines in the pathogenesis of rheumatoid arthritis–Practical and potential application of cytokines as biomarkers and targets of personalized therapy

E Brzustewicz, E Bryl - Cytokine, 2015 - Elsevier
… Moreover, cytokine network profiling is discussed in the context … the role of the cytokine
network in the pathogenesis of RA with … They can facilitate personalized therapy that provides the …

Serum cytokine measurements and biological therapy of psoriasis–Prospects for personalized treatment?

SM Solberg, LF Sandvik, M Eidsheim… - Scandinavian …, 2018 - Wiley Online Library
cytokines in the pathogenesis of psoriasis, TNF-α, IL-12/23 and IL-17 stand out as key cytokines
… The aim of this study was to investigate putative relationships between serum cytokines

Involvement of Il-33 in the pathogenesis and prognosis of major respiratory viral infections: future perspectives for personalized therapy

G Murdaca, F Paladin, A Tonacci, M Borro, M Greco… - Biomedicines, 2022 - mdpi.com
Interleukin (IL)-33 is a key cytokine involved in type-2 immunity and allergic airway disease. At
… In our work, we analyzed the pathogenetic and prognostic involvement of IL-33 during the …

Tuning monocytes and macrophages for personalized therapy and diagnostic challenge in rheumatoid arthritis

L Roszkowski, M Ciechomska - Cells, 2021 - mdpi.com
… various mediators responsible for inflammation and RA pathogenesis. On the other hand,
the … of different epigenetic regulations on inflammatory cytokines production by monocytes. In …

Inflammatory cytokines: from discoveries to therapies in IBD

I Marafini, S Sedda, V Dinallo… - … on biological therapy, 2019 - Taylor & Francis
… that can predict response to therapy and facilitate a personalized therapeutic approach, which
cytokines in IBD pathogenesis and provide an overview of the specific therapeutic options …

Pharmacogenomics of multiple sclerosis: in search for a personalized therapy

I Martinez-Forero, A Pelaez… - Expert opinion on …, 2008 - Taylor & Francis
pathogenic mechanisms at work in each individual might account for the lack of response to
therapy. It … are required to validate these cytokines in defining the response to IFN-β therapy. …

Multiple roles for cytokines in atopic dermatitis: from pathogenic mediators to endotype-specific biomarkers to therapeutic targets

L Fania, G Moretta, F Antonelli, E Scala… - International Journal of …, 2022 - mdpi.com
… of pathogenic mechanisms leading to AD. In this review, we discuss the role of cytokines in
the pathogenesis … Moreover, we describe the cytokine patterns in patients with AD at different …

The evaluation of cytokines to help establish diagnosis and guide treatment of autoinflammatory and autoimmune diseases

AL Chetaille Nézondet, PE Poubelle… - Journal of Leucocyte …, 2020 - academic.oup.com
therapies for this disabling disease. Several other autoimmune diseases affecting many
persons have relatively common pathogenesis … for a personalized therapeutic approach to avoid …

Moving towards personalized treatments of immune-related adverse events

K Esfahani, A Elkrief, C Calabrese, R Lapointe… - Nature reviews Clinical …, 2020 - nature.com
… Other therapeutic options to deplete pathogenic autoantibodies include plasmapheresis …
cytokines implicated in the development of irAEs 135 ; however, to our knowledge, therapeutic

Cytokines and soluble mediators as architects of tumor microenvironment reprogramming in cancer therapy

S Xu, Q Wang, W Ma - Cytokine & Growth Factor Reviews, 2024 - Elsevier
… Identifying specific cytokine and mediator pathways most amenable to therapeutic … for TME
profiling could enable more personalized therapeutic approaches, allowing for interventions …