… (1−3) bisindole alkaloids of the hamacanthin class and a new (6) bisindole alkaloid of the
topsentin … Herein we describe the structure elucidation and the evaluation of cytotoxicity and …

… cytotoxicity against various human cancer cell lines with IC 50 values of 2.71–16.22 μM. A
possible biosynthesis pathway toward the new bisindole alkaloids … are new bisindole alkaloids …

… bromotopsentin (3) shows cytotoxicity against the P388 cell … cytotoxicity against the human
leukemia cell line K-562 with an IC50 value of 0.6mg/ml.In our determination of the cytotoxicity …

… alkaloids were established by NMR and MS analysis. The bisindole alkaloids demonstrated
cytotoxicity … one monomeric indole alkaloid was found to be cytotoxic. Tabernaemontanine …

… The isolated bisindole alkaloids were cytotoxic to human MRC-5 and rat L-6 cell lines. The
biosynthetic origin of the α-amino aldehyde moiety in tabernaelegantinals was proposed as …

… of bisindole hybrids in the development of novel anticancer agents. In this review, we present
a brief account of the bisindole alkaloids … the cytotoxic activity of this bisindole alkaloid was …

… source of monoterpenoid indole and bisindole alkaloids with intriguing carbon skeletons …
bovina provided monomeric indole and bisindole alkaloids [8–10]. As a part of our research on …

… micromolar cytotoxicity against one or more of five human cancer cell lines. Bisindole alkaloids
have … important bisindole alkaloid vinblastine was established. (1) To date, hundreds of …

… This review will be confined to the bisindoles from plants … cytotoxic effects of the alkaloids
of M. euchrestifolia on human cancer cell lines, it was found that while the monomeric alkaloids …

… As part of a continuing search for new cytotoxic alkaloids, six new bisindole alkaloids and
two new monomeric indole alkaloids, as well as 29 known alkaloids, were isolated from the …