Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus

W Yi, D Chen, X Ding, X Li, S Li, Y Di, Y Zhang, X Hao - Fitoterapia, 2018 - Elsevier
indole alkaloids, were isolated from Melodinus tenuicaudatus and Melodinus khasianus (Melodinus
-type bisindole alkaloids while 7 is a novel melodinus-type alkaloid. Their structures …

Melokhanines A–J, Bioactive Monoterpenoid Indole Alkaloids with Diverse Skeletons from Melodinus khasianus

GG Cheng, D Li, B Hou, XN Li, L Liu… - Journal of Natural …, 2016 - ACS Publications
… The alkaloids were tested for antimicrobial activity, while the new compounds were also
tested for their in vitro cytotoxicity against SMMC-7721, MCF-7, HL-60, SW480, and A-549 …

A review on the genus Melodinus: traditional uses, phytochemical diversity and pharmacological activities of indole alkaloids

SF Teng, FR Li, QM Cui, A Khan, T He, XD Luo… - Phytochemistry …, 2023 - Springer
… In this review, a total of 345 indole alkaloids are reported and collected from 21 Melodinus
species, and are classified into … khasianus with unprecedented 6/5/6/4/6 rings. The iboga-type …

Cytotoxic indole alkaloids from Melodinus fusiformis and M. morsei

CAI Xiang-Hai, H JIANG, LI Yan, GG CHENG… - Chinese Journal of …, 2011 - Elsevier
indole alkaloids from the leaves and twigs of Melodinus fusiformis and M. morsei. METHODS:
The indole alkaloids … Their cytotoxicity were evaluated using the MTT method in 96-well …

Melotenuines AE, cytotoxic monoterpenoid indole alkaloids from Melodinus tenuicaudatus

JW Liu, ZQ Huo, Q Zhao, XJ Hao, HP He, Y Zhang - Fitoterapia, 2019 - Elsevier
indole alkaloids were isolated from the twigs and leaves of Melodinus tenuicaudatus. Reported
… are the isolation, structure elucidation, and cytotoxicity evaluation of the new alkaloids. …

Indole alkaloids: 2012 until now, highlighting the new chemical structures and biological activities

PF Rosales, GS Bordin, AE Gower, S Moura - Fitoterapia, 2020 - Elsevier
… 248–251 Melodinus tenuicaudatus and Melodinus khasianus 2018 Extracted with 95% MeOH
at room temperature. The crude extract was suspended in water and was defatted with PE …

Melognine, a novel monoterpenoid indole alkaloid from Melodinus fusiformis that induce apoptosis in BT549 cells

J Zhou, SY Du, ZY Fang, JH Feng - Natural Product Research, 2021 - Taylor & Francis
… , the cytotoxicity of melognine in K562, A549, PC3 and BT549 was evaluated by MTT assay.
Melognine showed significant cytotoxic … The above results indicated the cytotoxic activity of …

Phytochemical and pharmacological properties of the Genus Melodinus–a review

JH Jiang, WD Zhang, YG Chen - Tropical Journal of Pharmaceutical …, 2015 - ajol.info
… Some compounds show cytotoxic and anti-inflammatory activities. In this paper, we summarize
… In this paper, indole alkaloids could be classified into ten groups from some Melodinus

Cytotoxic melodinus-type alkaloids from the ethanol extract of Melodinus fusiformis

XP Tang, SQ Cao, Y Song, LS Zhou - Fitoterapia, 2016 - Elsevier
… of structurally diverse monoterpenoid indole alkaloids which were … monoterpenoid indole
alkaloids obtained from MelodinusMelodinus-type alkaloids, a subset of monoterpenoid indole

HRESIMS-guided isolation of aspidosperma-scandine type bisindole alkaloids from Melodinus cochinchinensis and their anti-inflammatory and cytotoxic activities

FR Li, L Liu, YP Liu, JT Wang, ML Yang, A Khan… - Phytochemistry, 2021 - Elsevier
Melodinus khasianus Hook.f.) is mainly distributed in Yunnan and Guizhou provinces of …
As an extension of our ongoing search for structurally unique and bioactive indole alkaloids, the …