[HTML][HTML] … of SARS-CoV-2 P. 1 (Gamma) lineage inducing the recent COVID-19 wave in southern Brazil and the finding of an additional S: D614A mutation

M Demoliner, MS da Silva, JS Gularte… - Infection, Genetics and …, 2021 - Elsevier
… a new S:D614A mutation. Newly mutations could be emerging due the quick SARS-CoV-2 …
variants vigilance is essential to the better management of the health SARS-CoV-2 crisis. …

Molecular Dynamics Studies on the structural characteristics for the stability prediction of SARS-CoV-2

KE Choi, JM Kim, JE Rhee, AK Park, EJ Kim… - International Journal of …, 2021 - mdpi.com
coronavirus 2 (SARS-CoV-2) affects the COVID-19 pandemic in the world. The spike protein
of the various proteins encoded in SARS-CoV-… mutants for spike protein (D614G and D614A-…

Characterizations of SARS-CoV-2 mutational profile, spike protein stability and viral transmission

S Laha, J Chakraborty, S Das, SK Manna… - Infection, genetics and …, 2020 - Elsevier
mutations in protein stability and viral transmission. We have identified frequently mutated
residues by aligning ~660 SARS-CoV-2 … Unlike D614A, V483A mutant is a part of the crucial …

Structural insights into the effect of mutations in the spike protein of SARS-CoV-2 on the binding with human furin protein

M Suleman, M Luqman, DQ Wei, S Ali, SS Ali, A Khan… - Heliyon, 2023 - cell.com
… while the D614A, V622F, and Q677H mutations were found in the central helices of the spike
protein. Based on the observation, G181V, G446V, D614A, and V622F mutants were found …

… of protein stability and allosteric interaction networks in distinct conformational forms of the SARS-CoV-2 spike D614G mutant: reconciling functional mechanisms …

GM Verkhivker, S Agajanian, D Oztas… - Journal of Biomolecular …, 2022 - Taylor & Francis
… and mutant SARS-CoV-2 spike proteins, providing evidence that the D614G mutation can
… Interestingly, D614A mutation in the closed and open states resulted in a small stabilization …

Predominance of SARS-CoV-2 P. 1 (Gamma) lineage inducing the recent wave in southern Brazil and the finding of an additional S: D614A mutation

M Demoliner, MS da Silva, JS Gularte, AW Hansen… - 2021 - researchsquare.com
… Whole genome sequencing of 71 SARS-CoV-2 samples shows a predominance of Gamma
… presented a D614A mutation. Newly mutations could be emerging due the quick SARS-CoV-…

[HTML][HTML] Mutations in human SARS-CoV-2 spike proteins, potential drug binding and epitope sites for COVID-19 therapeutics development

K Guruprasad - Current research in structural biology, 2022 - Elsevier
… site, a total of 4,729 distinct mutations were observed and are … to the SARS-CoV-2 spike
protein mutations identified in the … -2 spike protein sequences were; D614N, D614A, D614S. …

Mutational analysis of the spike protein of SARS-COV-2 isolates revealed atomistic features responsible for higher binding and infectivity

M Hanifa, M Salman, M Fatima, N Mukhtar… - Frontiers in Cell and …, 2023 - frontiersin.org
… seeks to identify the mutations found in the … SARS-COV-2 spike protein owing to the mutations
and determine the signature pattern. Mutational analysis of the spike protein in SARS-CoV-…

Molecular dynamics studies on the structural stability prediction of SARS-CoV-2 variants including multiple mutants

KE Choi, JM Kim, JE Rhee, AK Park, EJ Kim… - International Journal of …, 2022 - mdpi.com
… protein variants of SARS-CoV-2 in … mutants (D614G, D614A, L455F, F456L, and Q787H)
depending on the domain region. In our previous study [16], we showed that the D614G mutant

[HTML][HTML] Early introduction, dispersal and evolution of Delta SARS-CoV-2 in Southern Brazil, late predominance of AY. 99.2 and AY. 101 related lineages

JS Gularte, MS da Silva, ACS Mosena, M Demoliner… - Virus Research, 2022 - Elsevier
… Tracking SARS-CoV-2 variants through sequencing becomes … the mutational distribution and
signatures across the SARS-CoV-… Brazil and the finding of an additional S: D614A mutation