Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran
J Stangier, M Feuring - Blood coagulation & fibrinolysis, 2012 - journals.lww.com
… concentrations of dabigatran using regression analysis. Dabigatran's calibration curve for
thrombin clotting time was … thrombin clotting time in blank samples without dabigatran and in …
thrombin clotting time was … thrombin clotting time in blank samples without dabigatran and in …
… dabigatran concentration, as assessed using the direct thrombin inhibitor assay, and activated clotting time/activated partial thromboplastin time in patients with atrial …
K Okubo, T Kuwahara, K Takagi, M Takigawa… - The American Journal of …, 2015 - Elsevier
… dabigatran concentration and the clotting time that is measured using this assay. Although
the relation between clotting time and dabigatran … quantify dabigatran concentrations through …
the relation between clotting time and dabigatran … quantify dabigatran concentrations through …
Measurement of dabigatran plasma concentrations by calibrated thrombin clotting time in comparison to LC-MS/MS in human volunteers on dialysis
M Schmohl, D Gansser, V Moschetti, J Stangier - Thrombosis research, 2015 - Elsevier
… to measure dabigatran concentrations in … dabigatran concentrations within a range of 50–500
ng/ml. The objective of this study was to assess comparability of dabigatran concentrations …
ng/ml. The objective of this study was to assess comparability of dabigatran concentrations …
… of therapeutic levels of dabigatran in atrial fibrillation evaluated by thrombelastography (TEG®), Hemoclot Thrombin Inhibitor (HTI) assay and Ecarin Clotting Time …
S Solbeck, AS Jensen, C Maschmann… - … Journal of clinical …, 2018 - Taylor & Francis
… dabigatran 110 mg ×2 had a TEG ® R mean 14.2 min (range 9.1–25), a mean dabigatran
concentration … Our data indicate that variation in measured dabigatran concentrations by HTI, …
concentration … Our data indicate that variation in measured dabigatran concentrations by HTI, …
Impact of dabigatran on a large panel of routine or specific coagulation assays
J Douxfils, F Mullier, S Robert… - Thrombosis and …, 2012 - thieme-connect.com
… The preparation of dabigatran concentrations is presented in Supplementary materials (…
Ratio expressed the clotting time of a NPP spiked with dabigatran divided by the clotting time of …
Ratio expressed the clotting time of a NPP spiked with dabigatran divided by the clotting time of …
The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma …
G Hapgood, J Butler, E Malan… - Thrombosis and …, 2013 - thieme-connect.com
… (TT) has been shown to be extremely sensitive to the presence of dabigatran but is too
sensitive to quantify concentration (4, 11). The TT is useful in excluding the presence of …
sensitive to quantify concentration (4, 11). The TT is useful in excluding the presence of …
Effect of dabigatran on clotting time in the Clotpro Ecarin clotting assay: a prospective, single-arm, open-label study
AYY Fong, LL Tiong, SSN Tan… - Clinical and Applied …, 2020 - journals.sagepub.com
… The ecarin clotting assay (ECA), performed on the ClotPro viscoelastic … of dabigatran. We
assessed the association between trough plasma dabigatran concentration and clotting time (…
assessed the association between trough plasma dabigatran concentration and clotting time (…
Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis
KH Liesenfeld, HG Schäfer, IF Trocóniz… - British journal of …, 2006 - Wiley Online Library
… The relationship between patient ecarin clotting time (ECT) values and dabigatran plasma
concentrations 0–12 h after first administration of dabigatran etexilate following orthopaedic …
concentrations 0–12 h after first administration of dabigatran etexilate following orthopaedic …
Dabigatran effects on the international normalized ratio, activated partial thromboplastin time, thrombin time, and fibrinogen: a multicenter, in vitro study
WE Dager, RC Gosselin, S Kitchen… - Annals of …, 2012 - journals.sagepub.com
… dabigatran concentrations. For the aPTT, all reagents demonstrated decreasing sensitivity to
increasing dabigatran concentrations. … decrease with increasing dabigatran concentrations. …
increasing dabigatran concentrations. … decrease with increasing dabigatran concentrations. …
Measuring dabigatran concentrations using a chromogenic ecarin clotting time assay
RC Gosselin, DM Dwyre… - Annals of …, 2013 - journals.sagepub.com
… to improve sensitivity of the test at lower concentrations (<40 ng/mL) of the drug. We
describe our evaluation of chromogenic ECA for measuring serum dabigatran concentrations. …
describe our evaluation of chromogenic ECA for measuring serum dabigatran concentrations. …
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