Dabigatran etexilate and risk of myocardial infarction, other cardiovascular events, major bleeding, and all‐cause mortality: a systematic review and meta‐analysis of …

J Douxfils, F Buckinx, F Mullier, V Minet… - Journal of the …, 2014 - Am Heart Assoc
… No firm conclusion can be taken with the lower dabigatran etexilate dosage (110 mg BID)
because of the limited number of studies. However, a trend toward an increased risk of MI (33%…

The assessment of anticoagulant activity to predict bleeding outcome in atrial fibrillation patients receiving dabigatran etexilate

YT Chang, YF Hu, JN Liao, CM Chern… - Blood Coagulation & …, 2016 - journals.lww.com
… collection in the present study could predict the bleeding outcome, serial dabigatran
etexilate-HTI measurement might provide an even better predictive value. The routine coagulation …

Dabigatran etexilate

M Sanford, GL Plosker - Drugs, 2008 - Springer
… [19,20] The primary efficacy outcome was a composite … [19,20] Secondary efficacy outcomes
included a composite of major … sodium, focusing on the occurrence of bleeding[19,20] and …

The pharmacology and therapeutic use of dabigatran etexilate

S Sarah - The Journal of Clinical Pharmacology, 2013 - Wiley Online Library
… not result in a consistent effect on the relative risk of bleeding or a statistically significant effect
on the relative efficacy of either dose of dabigatran etexilate … rifampin, dabigatran exposure …

Safety and efficacy of dabigatran etexilate during catheter ablation of atrial fibrillation: a meta-analysis of the literature

SH Hohnloser, AJ Camm - Europace, 2013 - academic.oup.com
bleeding events constituted safety outcomes in all studies but there was no uniform definition
of these events. Major bleeding … rates of periprocedural bleeding of dabigatran and warfarin…

Dabigatran etexilate: a review in nonvalvular atrial fibrillation

HA Blair, GM Keating - Drugs, 2017 - Springer
… and bleeding outcomes associated with dabigatran etexilate versus warfarin administered
for the prevention of stroke or systemic embolism in nonvalvular atrial fibrillation. Results from …

Risk of bleeding with dabigatran in atrial fibrillation

I Hernandez, SH Baik, A Piñera… - JAMA internal medicine, 2015 - jamanetwork.com
… of major bleeding between treatments; however, dabigatran was … In addition, dabigatran
etexilate mesylate, 150 mg, was … Our results for gastrointestinal and intracranial bleeding are …

Dabigatran etexilate: an oral direct thrombin inhibitor for prophylaxis and treatment of thromboembolic diseases

BE Baetz, SA Spinler - Pharmacotherapy: The Journal of …, 2008 - Wiley Online Library
… Overall, results of several studies demonstrate dabigatran etexilate’s rapid onset of effect, …
in the frequency of major bleeding events between either dabigatran etexilate 220 mg (p=0.44) …

Dabigatran etexilate: a novel oral direct thrombin inhibitor

ML Blommel, AL Blommel - American Journal of Health-System …, 2011 - academic.oup.com
… higher rates of major bleeding. This study also found that dabigatran etexilate 150 mg twice
daily … difference in any bleeding outcomes between either of the dabigatran groups and the …

Efficacy and safety of dabigatran etexilate and warfarin in “real-world” patients with atrial fibrillation: a prospective nationwide cohort study

TB Larsen, LH Rasmussen, F Skjøth, KM Due… - Journal of the American …, 2013 - jacc.org
… We found no evidence of an excess of bleeding events or MI among dabigatran-treated patients
in this propensity-… The outcomes addressed in this study cover hospital diagnosis (major …