… Because circadian rhythms are found in most living organisms and the fact that DAF-16 and
… of NPs on circadian rhythms and stress resistance in higher organisms including humans. …

… Circadian rhythms regulate sleep … that DAF-16 FoxO is required for sleep bouts changes
in all three paradigms. However, arousal threshold changes are not dependent on DAF-16 …

… The circadian clock machinery orchestrates organism … For unknown reasons, there is a
decline in circadian rhythms with … the complex links between the circadian clock, metabolic (dys…

… the function of the DAF-16/FOXO transcription factor in neurons, but not that of NPR-1.
Conversely, response to weak stimuli did not require the function of DAF-16/FOXO. These findings …

… Subsequently, we show binding of FOXO3 to two Daf-binding elements (DBEs) located in
the Clock promoter area, implicating Clock as a transcriptional target of FOXO3. …

… (hence the name “circadian”). A less investigated but nonetheless critical characteristic of
circadian clocks is the synchronization or entrainment of the circadian rhythm to exactly 24 h …

… Circadian rhythms are found in organisms living under extreme conditions, including … In
summary, we have demonstrated a clear diurnal and circadian rhythm of stress tolerance to two …

… Rather than endogenous circadian rhythms, we 117 identify a greater prevalence of genes
… circadian rhythms associated with stress resistance decline and 818 modulated by DAF-16 …

… daf-12 to select S3 or S3d alternatives.daf-12 together with other heterochronic genes acts
in cells downstream of organismal commitments. daf-… programs, whereas daf-12b activity is …

… To determine the subcellular localization of DAF-16 we used the strains expressing the
fluorescently tagged version of DAF-16 (DAF-16::GFP) described above. At the indicated times, …