Factors associated with damage accrual in patients with systemic lupus erythematosus with no clinical or serological disease activity: a multicentre cohort study

D Apostolopoulos, R Kandane-Rathnayake… - The Lancet …, 2020 - thelancet.com
… by glucocorticoid use in active disease. We sought to determine the … to damage accrual
from associations with disease activity by analysing patients without measurable disease activity. …

High disease activity status suggests more severe disease and damage accrual in systemic lupus erythematosus

R Koelmeyer, HT Nim, M Nikpour, YB Sun… - Lupus science & …, 2020 - lupus.bmj.com
… Conclusions HDAS is associated with more severe disease, as measured by higher disease
activity across time, corticosteroid exposure and damage accrual. The occurrence of HDAS …

Both prolonged remission and Lupus Low Disease Activity State are associated with reduced damage accrual in systemic lupus erythematosus

MWP Tsang-A-Sjoe, IEM Bultink, M Heslinga… - …, 2016 - academic.oup.com
… to identify predictors for damage accrual. Secondly, we assessed the relationship between
both prolonged disease remission and low disease activity and damage accrual in a cohort of …

Damage accumulation in systemic lupus erythematosus and its relation to disease activity and mortality.

A Becker-Merok, HC Nossent - The Journal of rheumatology, 2006 - jrheum.org
… Global disease activity was the main determinant of damage accrual. Accrued damage was
not an independent risk factor for death, which was predicted by age > 40 years and WAS > 3…

Remission and low disease activity (LDA) prevent damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International …

MF Ugarte-Gil, J Hanly, M Urowitz, C Gordon… - … rheumatic diseases, 2022 - ard.bmj.com
… of the impact of disease activity states on organ damage accrual are depicted in table 4. …
disease activity state on global damage accrual as well as on specific organ damage accrual. …

Association of achieving lupus low disease activity state fifty percent of the time with both reduced damage accrual and mortality in patients with systemic lupus …

C Sharma, W Raymond, G Eilertsen… - Arthritis care & …, 2020 - Wiley Online Library
Objective To assess the impact of achieving Lupus Low Disease Activity State ≥50% of the
time ( LLDAS ‐50) on damage accrual and mortality in an inception cohort of patients with …

Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic …

M Piga, A Floris, G Cappellazzo, E Chessa… - Arthritis research & …, 2017 - Springer
… on damage development, we consider 7.5 mg/day an acceptable cutoff to define low disease
activity … risk of steroid-related damage during maintenance therapy in patients with SLE. …

Independent association of glucocorticoids with damage accrual in SLE

D Apostolopoulos, R Kandane-Rathnayake… - Lupus science & …, 2016 - lupus.bmj.com
… They did not report the contribution of disease activity to damage accrual, and disease
activity was integrated into multivariate analysis using mean SLEDAI as opposed to the more …

Disease activity and damage accrual during the early disease course in a multinational inception cohort of patients with systemic lupus erythematosus

J Nossent, E Kiss, B Rozman, G Pokorny… - Lupus, 2010 - journals.sagepub.com
accrued damage (SDI ≥1) for which baseline presence of proteinuria and persistent disease
activity … reductions in disease activity and improved mortality, the risk for disease flare and …

Association of serum MIP-1α, MIP-1β, and RANTES with clinical manifestations, disease activity, and damage accrual in systemic lupus erythematosus

LM Vilá, MJ Molina, AM Mayor, JJ Cruz… - Clinical …, 2007 - Springer
… Pearson r correlation test was used to evaluate the chemokine variations with the disease
activity (per SLAM) and the damage accrual (per SDI). The significance level of less than 0.05 …