… More recently, serrated colorectal polyps (hyperplastic polyps, sessile … of colorectal
carcinogenesis in humans. Archival sections from early experiments in Sprague-Dawley (SD) rats …

… Whether the Sprague-Dawley rat in our country differs genetically from the Sprague-Dawley
rat … Rubio CA, Nylander G, Santos M: Experimental colon cancer in the absence of intestinal …

… anism of colorectal carcinogenesis. Naturally occurring substances in the intestinal contents,
… carcinogens for the colon mucosa (l). Protracted consumption of fat or beef may change the …

… In conclusion, we must consider whether AOM-induced colon cancer in the rat is a good
model for human disease. The pathological analysis described here shows good evidence for a …

… The main objective or the present proposal was to investigate the effect of feeding a low- or
high-fat diet in the early and late stages of colon carcinogenesis. Sprague-Dawley male rats …

… Aberrant crypts used in this study were induced in male Sprague—Dawley rats by a single
ip injection of the colon carcinogen AOM at a dose of 20 mg/kg body wt. The animals were fed …

… the carcinogen-induced colon cancer SpragueDawley rat … induces NQO1 in the colons of
these rats without inducing other … colon cancer University of Manitoba Sprague-Dawley rat …

… carried out a long-term study in rats fed the standard American Institute of Nutrition … rats,20
Sprague Dawley rats, and 40 OF1 mice were all given initiating dose(s) of colon carcinogen, …

… colorectal carcinoma (CRC) extend to 1963, when Laqueur discovered that rats fed cycasin,
a plant product, developed intestinal cancer… even more potent intestinal carcinogens.Today, …

… The effect on intestinal carcinogenesis of feeding a 20% wheat bran dietary … of carcinogen
administration with 1,2-dimethylhydrazine, was ex amined in 48 male Sprague-Dawley rats …