Modafinil improves functional outcomes in patients with residual excessive sleepiness associated with CPAP treatment

TE Weaver, ER Chasens, S Arora - Journal of Clinical Sleep …, 2009 - jcsm.aasm.org
… In total, the analysis included 480 patients—292 in the modafinil group and 188 in the
placebo group (safety analysis set). FOSQ efficacy data were available for 442 patients: 263 for …

The increasing lifestyle use of modafinil by healthy people: safety and ethical issues

SP Mann, BJ Sahakian - Current Opinion in Behavioral Sciences, 2015 - Elsevier
… of modafinil, a recently synthesized wake-promoting drug, on healthy individuals. Modafinil
… It may be favorable only in circumstances of excessive fatigue or pressure not manageable …

… study of the safety and maintenance of efficacy of solriamfetol (JZP-110) in the treatment of excessive sleepiness in participants with narcolepsy or obstructive sleep …

A Malhotra, C Shapiro, JL Pepin, J Hedner, M Ahmed… - Sleep, 2020 - academic.oup.com
… efficacy and safety profile in narcolepsy [18]. In the United States, modafinil and armodafinil
… Although modafinil and armodafinil clearly have efficacy, there are some patients in whom …

Effects of modafinil and armodafinil in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials

YC Kuan, D Wu, KW Huang, NF Chi, CJ Hu… - Clinical …, 2016 - Elsevier
modafinil and armodafinil significantly improved subjective and objective daytime sleepiness
Regarding safety profiles and AEs, both modafinil and armodafinil were well-tolerated by …

Toxicity from modafinil ingestion

HA Spiller, D Borys, JRK Griffith… - Clinical …, 2009 - Taylor & Francis
Modafinil is a non-amphetamine stimulant the Food and Drug Administration (FDA) approved
in 1998 to improve excessive sleepiness … Neither efficacy nor safety has been established …

Effects of modafinil on cognitive performance and alertness during sleep deprivation

NJ Wesensten - Current pharmaceutical design, 2006 - ingentaconnect.com
modafinil to include improving wakefulness in patients with excessive sleepiness associated
with shift work sleep … More information on modafinil’s safety profile is provided in the product …

Modafinil improves real driving performance in patients with hypersomnia: a randomized double-blind placebo-controlled crossover clinical trial

P Philip, C Chaufton, J Taillard, A Capelli, O Coste… - Sleep, 2014 - academic.oup.com
sleep apnea syndrome (OSAS). Narcolepsy and idiopathic hypersomnia (IH) induce severe
excessive daytime sleepiness but … Patients from this group can therefore be defined as safe

Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial

Y Dauvilliers, C Bassetti, GJ Lammers, I Arnulf… - The Lancet …, 2013 - thelancet.com
… Our findings suggest that excessive daytime sleepiness can be improved by pitolisant for at
… and safety findings to these populations. Furthermore, patients who had previously received …

A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness …

M Fava, ME Thase, C DeBattista - Journal of Clinical Psychiatry, 2005 - psychiatrist.com
modafinil augmentation in major depressive disorder (MDD) patients with fatigue and excessive
sleepiness … The safety/tolerability data from this study suggest that modafinil treatment is …

Safety profile of modafinil across a range of prescribing indications, including off-label use, in a primary care setting in England: results of a modified prescription-event …

M Davies, L Wilton, S Shakir - Drug safety, 2013 - Springer
… the long-term effects and safety profile of modafinil in children. One small study (… modafinil
in the treatment of excessive daytime sleepiness (EDS) in children. This study found modafinil