… In summary, DDX5 and DDX17 regulate tumorigenesis and tumor progression by
participating in RNA metabolism, regulating posttranslational modifications, acting on tumor-related …

… Complicated signaling pathways are demonstrated for the regulation of miRNA biogenesis.
One of the focal points of this regulation is DDX5/DDX17 [10]. DDX5 is shown to interact with …

… regulation [[8], [9], [10], [11]]. In human malignancies, many studies have detected the
overexpression of DDX5 and confirmed its involvement in tumorigenesis, … with the regulation of …

… DDX5 is implicated in cell cycle regulation and apoptosis [56]. Not unexpectedly, alterations
in DDX5 metabolism are linked to tumorigenesis… the RNA helicases DDX5 and DDX17 are …

… DDX5 and DDX17 are multitasking proteins that regulate … , an emerging view is that DDX5
and DDX17 may act through … We will also discuss the potential roles of DDX5 and DDX17 …

… Furthermore, we explored possible signaling pathways that DDX5 regulated in HCC. …
down-regulated in the context of depletion DDX5 in HCC cells, indicating that DDX5-mediated Akt …

… DDX5/DDX17-regulated exons by RT-PCR, we observed that class I exons had a low
basal inclusion rate in control … inclusion rate of DDX5/DDX17-regulated exons using gene-…

… a role in gene expression level regulation when it is coupled to the … ddx5 and ddx17 have
a dual role in the control of the pro-migratory NFAT5 transcription factor. First, ddx5 and ddx17 …

… regulate their coactivation potential, binding to known interactants or protein stability. Knock-out
mouse models revealed that both DDX5 and DDX17 … /p72 promote tumorigenesis and …

… A pro-differentiation role has been proposed by the finding that DDX5 and DDX17 coactivate
the myogenic regulatory factor myoblast determination protein 1 (MyoD) and are required …