Distinct functional microcircuits in the nucleus accumbens underlying goal-directed decision-making

EA West, TM Moschak, RM Carelli - Goal-Directed Decision Making, 2018 - Elsevier
… are involved in goal-directed decision-making, the nucleus accumbens (NAc) is … core and
shell in goal-directed decision-making. Distinct functional roles of the nucleus accumbens core

[HTML][HTML] Contributions of the nucleus accumbens and its subregions to different aspects of risk-based decision making

CM Stopper, SB Floresco - Cognitive, Affective, & Behavioral …, 2011 - Springer
… Furthermore, our findings reveal that the NAc shell, rather than the core, seems to play a
more critical role in guiding this form of decision making, whereas neural activity in the core

Nucleus accumbens neurons track behavioral preferences and reward outcomes during risky decision making

JA Sugam, MP Saddoris, RM Carelli - Biological psychiatry, 2014 - Elsevier
… Average population responses for excitatory (A–C) and inhibitory (D–F) cue-related neural
activity in the nucleus accumbens core. Cue onset is indicated by C on x axis; duration is …

… D1/D2 receptor activity in the nucleus accumbens core but not in the nucleus accumbens shell and orbitofrontal cortex modulates risk-based decision making

B Mai, S Sommer, W Hauber - International Journal of …, 2015 - academic.oup.com
Background: It is well known that brain dopamine (DA) signals support risk-based decision
making; however, the specific terminal regions of midbrain DA neurons through which DA …

Phasic nucleus accumbens dopamine encodes risk-based decision-making behavior

JA Sugam, JJ Day, RM Wightman, RM Carelli - Biological psychiatry, 2012 - Elsevier
… NAc core (… core in appropriate decision making based on risk (17). Given these findings,
our study was focused on examining DA release in the NAc core during risky decision making. …

[HTML][HTML] Rapid dopamine dynamics in the accumbens core and shell: learning and action

MP Saddoris, JA Sugam, F Cacciapaglia… - Frontiers in bioscience …, 2013 - ncbi.nlm.nih.gov
… To test this, recent work in our laboratory used a risky decision making task (125). In this task,
animals had the option of pressing one lever (FR1) for 1 sucrose pellet 100% of the time, or …

Differential contributions of nucleus accumbens subregions to cue-guided risk/reward decision making and implementation of conditional rules

SB Floresco, DR Montes, MT Maric… - Journal of …, 2018 - Soc Neuroscience
… A primary objective of this study was to explore how the NAc core and shell contribute to
risk/reward decision making under conditions where discriminative stimuli inform about the …

[HTML][HTML] Motivational states influence effort-based decision making in rats: the role of dopamine in the nucleus accumbens

B Mai, S Sommer, W Hauber - Cognitive, Affective, & Behavioral …, 2012 - Springer
decision making. Here we examined whether dopamine (DA) in the nucleus accumbens
core (AcbC) modulates the effects of motivational states on effort-based decision making. Using …

Differential effects on effort discounting induced by inactivations of the nucleus accumbens core or shell.

S Ghods-Sharifi, SB Floresco - Behavioral neuroscience, 2010 - psycnet.apa.org
… of the nucleus accumbens (NAc) core and shell to effort-based decision making using a …
Furthermore, the contributions by the NAc core to this form of decision making can be …

Nucleus accumbens core and shell inactivation differentially affects impulsive behaviours in rats

M Feja, L Hayn, M Koch - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
… In contrast to our findings, a very recent study found that inactivation of the accumbens core
did not induce but rather decrease delay discounting in rats and that the effect of inactivation …