Development of Magnet‐Driven and Image‐Guided Degradable Microrobots for the Precise Delivery of Engineered Stem Cells for Cancer Therapy

T Wei, J Liu, D Li, S Chen, Y Zhang, J Li, L Fan, Z Guan… - Small, 2020 - Wiley Online Library
… -guided magnet-driven degradable microrobots to deliver engineered stem cells onto the
desired … The microrobots were designed to meet the requirements of degradability, mechanical …

A biodegradable magnetic microrobot based on gelatin methacrylate for precise delivery of stem cells with mass production capability

S Noh, S Jeon, E Kim, U Oh, D Park, SH Park, SW Kim… - Small, 2022 - Wiley Online Library
biodegradable microrobot (hereafter GelMA microrobot) fabricated with a simple microfluidic
device; the GelMA microrobot was designed for stem cell … Human nasal turbinate stem cells (…

Biodegradable microrobots and their biomedical applications: a review

J Li, J Yu - Nanomaterials, 2023 - mdpi.com
… During the degradation of cell-loaded microrobots, human nasal turbinate stem cells (hNTSCs)
and superparamagnetic iron oxide nanoparticles (SPIONs) are released. To stimulate the …

Multifunctional biodegradable microrobot with programmable morphology for biomedical applications

G Go, A Yoo, HW Song, HK Min, S Zheng, KT Nguyen… - ACS …, 2020 - ACS Publications
… of numerous mouse macrophages and human adipose-derived mesenchymal stem cells
(hADMSCs) into Mag-C. As a feasibility test of the use of cell-loaded Mag-C for liver cancer …

Magnetic nano-particles retrievable biodegradable hydrogel microrobot

D Kim, H Lee, S Kwon, H Choi, S Park - Sensors and Actuators B: Chemical, 2019 - Elsevier
microrobots for drug delivery, we propose a novel, biodegradable hydrogel microrobot in
which the remnant MNPs from the … such as stem cells as well as drugs for treating cancer cells. …

Using decellularized magnetic microrobots to deliver functional cells for cartilage regeneration

H Huang, J Li, C Wang, L Xing, H Cao, C Wang… - Small, 2024 - Wiley Online Library
… Human bone marrow mesenchymal stem cells are selected for their therapeutic potential in
OA … The degradation results showed that M-CEDSs are degradable in natural environments …

Human adipose–derived mesenchymal stem cell–based medical microrobot system for knee cartilage regeneration in vivo

G Go, SG Jeong, A Yoo, J Han, B Kang, S Kim… - Science Robotics, 2020 - science.org
… the PEI-coated MNPs are not biodegradable and cause cell death and inhibition of cell (17). …
it is hence a polymer suitable for the microrobot stem cell delivery for cartilage regeneration. …

3D‐Printed microrobotic transporters with recapitulated stem cell niche for programmable and active cell delivery

IC Yasa, AF Tabak, O Yasa, H Ceylan… - Advanced Functional …, 2019 - Wiley Online Library
… steerable microrobotic cell transporter (MCT) for stem cell delivery within a recapitulated cell
… of MCTs are biodegradable and can be remodeled by the cells. To render overall structure …

Biodegradable microrobots for targeting cell delivery

P TirgarBahnamiri, S Bagheri-Khoulenjani - Medical Hypotheses, 2017 - Elsevier
… In addition the main problem in stem cell therapy is the fact that when cells are injected into
the body, there is no control on their final site of action and their faith. It has been suggested …

Development of a Cell‐Loading Microrobot with Simultaneously Improved Degradability and Mechanical Strength for Performing In Vivo Delivery Tasks

T Wei, J Li, L Zheng, C Wang, F Li… - Advanced Intelligent …, 2021 - Wiley Online Library
microrobots. This article proposes a new design that can result in 3D cell culture microrobots
with improved degradability … mesenchymal stem cells (MSCs) with microrobots was also …