Immediate hypothermia is not neuroprotective after severe hypoxia-ischemia and is deleterious when delayed by 12 hours in neonatal rats
H Sabir, E Scull-Brown, X Liu, M Thoresen - Stroke, 2012 - Am Heart Assoc
… Hypothermia (HT) for neonatal hypoxic-ischemic encephalopathy is advised to start within …
than against severe hypoxic-ischemic encephalopathy, but it is unknown whether delayed HT …
than against severe hypoxic-ischemic encephalopathy, but it is unknown whether delayed HT …
Delayed effects of severe hypoxia experienced by marine gastropod embryos
CJ Segura, OR Chaparro, JA Pechenik… - Marine Ecology …, 2014 - int-res.com
… per female and severely compromised juvenile growth and … of severe hypoxic conditions
can have a dramatic impact on early development and reproductive fitness, with some effects …
can have a dramatic impact on early development and reproductive fitness, with some effects …
Delayed cerebral atrophy following moderate hypoxia-ischemia in the immature rat
R Geddes, RC Vannucci, SJ Vannucci - Developmental neuroscience, 2001 - karger.com
… This study examined the effects of both severe and moderate duration of H/I on the evolution
of damage through 8 weeks of recovery. Seven-day-old rat pups were subjected to either …
of damage through 8 weeks of recovery. Seven-day-old rat pups were subjected to either …
Excitotoxicity in neonatal hypoxia
MV Johnston - Mental retardation and developmental …, 2001 - Wiley Online Library
… Caspase inhibitor affords neuroprotection after delayed administration in a rat model of
neonatal hypoxic-ischemic brain injury. J Clin Invest 101:1992–1999. Choi DW, Rothman SM. …
neonatal hypoxic-ischemic brain injury. J Clin Invest 101:1992–1999. Choi DW, Rothman SM. …
Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms
… suddenly and dramatically decreased SBP, whereas moderate hypoxia resulted in a delayed
and gradual decrease. This might be explained by differential alternations in the circadian …
and gradual decrease. This might be explained by differential alternations in the circadian …
[HTML][HTML] Mild hypothermia after severe transient hypoxia-ischemia reduces the delayed rise in cerebral lactate in the newborn piglet
PN Amess, J Penrice, EB Cady, A Lorek… - Pediatric …, 1997 - nature.com
… The severity of the primary insult (judged from the time integral of depletion of [NTP]/[EPP]) …
after a severe acute cerebral hypoxic-ischemic insult reduces the delayed elevation in lactate …
after a severe acute cerebral hypoxic-ischemic insult reduces the delayed elevation in lactate …
The effect of hypoxia in development
WS Webster, D Abela - Birth Defects Research Part C: Embryo …, 2007 - Wiley Online Library
… The use of hypoxia probes in mammalian embryos during the … of partial hypoxia, and this
may be essential to control cardiovascular development, perhaps under the control of hypoxia‐…
may be essential to control cardiovascular development, perhaps under the control of hypoxia‐…
Delayed hypoxemia after traumatic brain injury exacerbates long-term behavioral deficits
MK Davies, A Jacobs, DL Brody… - Journal of neurotrauma, 2018 - liebertpub.com
… hypoxemia and brain hypoxia occurring in the intensive care setting. Understanding long-term
effects of delayed hypoxemia … therapeutics targeting secondary brain hypoxia. For this …
effects of delayed hypoxemia … therapeutics targeting secondary brain hypoxia. For this …
[HTML][HTML] Severe hypoxemia: which strategy to choose
D Chiumello, M Brioni - Critical Care, 2016 - Springer
… -to-severe ARDS or in the presence of other organ failure, noninvasive ventilatory support
presents a high risk of failure: in those cases the risk/benefit of delayed mechanical ventilation …
presents a high risk of failure: in those cases the risk/benefit of delayed mechanical ventilation …
“Therapeutic time window” duration decreases with increasing severity of cerebral hypoxia–ischaemia under normothermia and delayed hypothermia in newborn …
O Iwata, S Iwata, JS Thornton, E De Vita, A Bainbridge… - Brain research, 2007 - Elsevier
… The influences of HI severity on latent-phase duration and regional neuroprotection … delayed
whole-body cooling to 35 and 33 C we aimed to assess relationships between HI severity …
whole-body cooling to 35 and 33 C we aimed to assess relationships between HI severity …
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