The Delta and Omicron variants of SARS-CoV-2: what we know so far

VP Chavda, R Bezbaruah, K Deka, L Nongrang… - Vaccines, 2022 - mdpi.com
… variant, which was mentioned earlier to be among the most prevalent strains of SARS-CoV-2
to exist to date. The variant is known to have several mutations at 22 different amino acids …

Molecular detection of SARSCoV‐2 and differentiation of Omicron and Delta variant strains

WNT Tsui, V Hamill, L Noll, N Lu… - Transboundary and …, 2022 - Wiley Online Library
SARS-CoV-2 strains including Delta and Omicron variants, but differentiates only the Delta
variant, not the Omicron … majority of the SARS-CoV-2 strains, and differentiate both Delta and …

Omicron and Delta variant of SARSCoV‐2: a comparative computational study of spike protein

S Kumar, TS Thambiraja, K Karuppanan… - Journal of medical …, 2022 - Wiley Online Library
… To combat some emerging SARS-CoV-2 strains, new vaccinations … Delta variant form. The
purpose of this study was to compare the binding affinity of SARS-CoV-2 Delta and Omicron

SARS-CoV-2 Omicron strain exhibits potent capabilities for immune evasion and viral entrance

X Zhang, S Wu, B Wu, Q Yang, A Chen, Y Li… - Signal transduction and …, 2021 - nature.com
… In this report, we first demonstrated that the newly emerging SARS-CoV-2 Omicron variant
significantly escaped from the neutralization of convalescent sera from early strain- or Delta- …

SARS-CoV-2 Omicron-B. 1.1. 529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19

EG Bentley, A Kirby, P Sharma, A Kipar, DF Mega… - BioRxiv, 2021 - biorxiv.org
… In this study, infection with the SARS-CoV-2 Omicron variant led to less severe weight loss,
lower viral loads in oral swabs, lungs and nasal tissue and less severe pathological changes …

Molecular detection of SARSCoV‐2 strains and differentiation of Delta variant strains

V Hamill, L Noll, N Lu, WNT Tsui… - Transboundary and …, 2022 - Wiley Online Library
… and 280 Omicron variant strains, were downloaded and analyzed for their in … all SARS-CoV-2
strains, including 98.6% of Omicron strains (Table 2). The coverage to the Omicron strains

COVID‐19 severity from Omicron and Delta SARSCoV‐2 variants

JO Wrenn, SB Pakala, G Vestal… - Influenza and other …, 2022 - Wiley Online Library
… of infections caused by these two strains, confirmed by whole genome … from SARS-CoV-2
positive patients at a large medical center. We found that infections caused by the Omicron

… simulations highlight the altered binding landscape at the spike-ACE2 interface between the Delta and Omicron variants compared to the SARS-CoV-2 original strain

E Pitsillou, JJ Liang, RC Beh, A Hung… - Computers in Biology …, 2022 - Elsevier
… the binding characteristics of the Delta and Omicron (BA.1) variants … Delta and Omicron were
found to bind to ACE2 with similar … to be energetically favourable in Omicron. In contrast to …

From delta to Omicron: S1-RBD/S2 mutation/deletion equilibrium in SARS-CoV-2 defined variants

V Papanikolaou, A Chrysovergis, V Ragos, E Tsiambas… - Gene, 2022 - Elsevier
… According to comparative genomic analyses combined with evolutionary tree synthesis,
the initial SARS-Cov-2 virus strain belongs to lineage b of beta-CoV genus. It also shares a …

The emergence and epidemic characteristics of the highly mutated SARSCoV‐2 Omicron variant

D Tian, Y Sun, H Xu, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
… twice as many as the Delta variant. Studies have … Omicron variant compared with the early
wild-type strain and the other four VOCs. The Omicron variant is becoming the dominant strain