… B7-H1 and the observation that activated DC and T cells express membrane-bound B7-H1
we investigated whether immune cells have the capacity to release sB7-H1. Understanding …

… myeloid dendritic cells (MDCs) express B7-H1, a member of the B7 family, on the cell surface.
… B7-H1 can be upregulated in various types of cells 12,17 , however. Here, we show that …

… Although dysfunctional dendritic cells contribute to inadequate … B7-H1 expression on
circulating myeloid dendritic cells (… We found that B7-H1 expression is significantly up-regulated …

… In an effort to identify immunoregulatory molecules on dendritic cells (DC), we generated
and screened for mAbs capable of modulating the T cell stimulatory function of DC. A …

… Induced B7-H1 expression in the tumor microenvironment … Antibody blockade of the B7-H1/PD-1
interaction overcomes … to cancer cells, B7-H1 is expressed on dendritic cells (DCs), …

… the T cell side (31). We have recently demonstrated that B7-H1 is critically involved in the
induction and maintenance of T cell anergy induced by IL-10-treated DC (24). Yet, blocking of …

… T-cell responses were impaired in B7-H1-deficient (B7-H1 −/… by transferring B7-H1-expressing
naïve T cells into B7-H1 −/− … with B7-H1-expressing naïve T cells also restored CD8 T-cell …

… − T cells … B7-H1 and B7-DC more than other B7 family members, whereas it was severely
impaired under inflammatory conditions. In conclusion, our findings suggest that B7-H1 and B7-…

… -H3 contributes to the reduced allostimulatory activity, we added anti-B7-H3 Ab and anti-B7-H1
Ab to the MLR (Fig. 1C, D). In these experiments we detected a substantial increase in T …

… the priming of T cells and poly(I:C) has the potential to up-regulate B7-H1 in both migratory
… whether B7-H1 on different DC subsets will affect CD8 T cell priming. We introduced B7-H1 …