Dendritic cell-based cancer immunotherapy

EG Engleman - Seminars in oncology, 2003 - Elsevier
… These studies show that antigen-loaded dendritic cell vaccinations are safe and promising
in the treatment of cancer. This review discusses the use of dendritic cells in immunotherapy …

Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation

U Švajger, N Obermajer, M Jeras - Immunology, 2010 - Wiley Online Library
Dendritic cells (DCs) are a functionally diverse cell type and represent the most potent
antigen-presenting cells of the … Resveratrol treatment generates dendritic cells (DCs) capable of …

Prednisolone treatment induces tolerogenic dendritic cells and a regulatory milieu in myasthenia gravis patients

C Luther, E Adamopoulou, C Stoeckle… - The Journal of …, 2009 - journals.aai.org
… Indeed, prednisolone treatment prevents LPS-induced maturation of monocyte-derived dendritic
cells by … In addition, CD4 + T cells cultured in the presence of such tolerogenic dendritic

Effectiveness and safety of chemotherapy combined with cytokine-induced killer cell/dendritic cell–cytokine-induced killer cell therapy for treatment of gastric cancer in …

Y Mu, CH Zhou, SF Chen, J Ding, YX Zhang, YP Yang… - Cytotherapy, 2016 - Elsevier
… -induced killer cells (CIKs) [10] and other immune cells, provides a new approach for
cancer treatment, considered as fourth-line cancer therapy [11], [12]. CIKs or dendritic cells (DCs) …

Tolerogenic dendritic cells

MC Takenaka, FJ Quintana - Seminars in immunopathology, 2017 - Springer
Dendritic cells (DCs) are pivotal regulators of the immune response, specialized in antigen
presentation to drive T cell … development of novel strategies for the treatment of autoimmunity. …

Pharmacological induction of tolerogenic dendritic cells and regulatory T cells

L Adorini, N Giarratana, G Penna - Seminars in immunology, 2004 - Elsevier
… CD25 + Treg cells able to inhibit the T-cell response to a … T cells are also induced by
treatment of adult non-obese … This treatment arrests insulitis, blocks the progression of Th1 cell

Integration of autologous dendritic cell-based immunotherapy in the primary treatment for patients with newly diagnosed glioblastoma multiforme: a pilot study

H Ardon, S Van Gool, IS Lopes, W Maes, R Sciot… - Journal of neuro …, 2010 - Springer
… We integrated immunotherapy in the primary standard treatment for eight pilot adult patients
… lysate-loaded monocyte-derived dendritic cells were given after radiochemotherapy. Boost …

Dendritic cells: emerging pharmacological targets of immunosuppressive drugs

H Hackstein, AW Thomson - Nature Reviews Immunology, 2004 - nature.com
… of dendritic cells (DCs). Here, we review our present understanding of how classical and
new immunosuppressive agents interfere with DC development and function. This knowledge …

… the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment

L Gabriele, P Borghi, C Rozera, P Sestili, M Andreotti… - Blood, 2004 - ashpublications.org
… and activity of monocyte-derived dendritic cells (DCs) from CML patients as well as in
modulation of the cell response to lipopolysaccharide (LPS). Treatment of CML monocytes with IFN…

Dendritic cell-based vaccines: barriers and opportunities

JA Cintolo, J Datta, SJ Mathew, BJ Czerniecki - Future oncology, 2012 - Taylor & Francis
Dendritic cells (DCs) have several characteristics that make them an ideal vehicle for tumor
vaccines, and with the first US FDA-approved DC-based vaccine in use for the treatment of …