Efficacy of vaccination with tumor-exosome loaded dendritic cells combined with cytotoxic drug treatment in pancreatic cancer
L Xiao, U Erb, K Zhao, T Hackert, M Zöller - Oncoimmunology, 2017 - Taylor & Francis
… with tumor-exosome (TEX)-loaded dendritic cells (DC) can be improved by combining with
drugs affecting myeloid-derived suppressor cells (MDSC). Experiments were performed with …
drugs affecting myeloid-derived suppressor cells (MDSC). Experiments were performed with …
Differential functional effects of biomaterials on dendritic cell maturation
J Park, JE Babensee - Acta biomaterialia, 2012 - Elsevier
… The immunological outcome of dendritic cell (DC) treatment … Treatment of DCs with PLGA
or chitosan films supported DC … Dendritic cells treated with HA film expressed lower levels of …
or chitosan films supported DC … Dendritic cells treated with HA film expressed lower levels of …
Role of dendritic cells in the induction of regulatory T cells
… Dendritic cells (DCs) play a key role in initiating immune responses and maintaining immune
… VDR is expressed on immune cells such as DCs and Vitamin D treatment of DC inhibits …
… VDR is expressed on immune cells such as DCs and Vitamin D treatment of DC inhibits …
Combination strategies to optimize efficacy of dendritic cell-based immunotherapy
M Van Gulijk, F Dammeijer, JGJV Aerts… - Frontiers in …, 2018 - frontiersin.org
… treatment with DCs and cytokine-induced killer cells (CIK) combined with bortezomib and
dexamethasone improved CD4 + /CD8 + T-cell ratios compared to baseline and treatment with …
dexamethasone improved CD4 + /CD8 + T-cell ratios compared to baseline and treatment with …
The treatment of patients with disseminated malignant melanoma by vaccination with autologous cell hybrids of tumor cells and dendritic cells
SW Krause, C Neumann, A Soruri, S Mayer… - Journal of …, 2002 - journals.lww.com
… to be subject to T cell-mediated immunity ( 1 ) and, therefore, is a candidate for vaccination
approaches. Dendritic cells (DC) are very potent immunostimulatory cells and due to this …
approaches. Dendritic cells (DC) are very potent immunostimulatory cells and due to this …
Clinical trials with combination of cytokine-induced killer cells and dendritic cells for cancer therapy
F Garofano, MA Gonzalez-Carmona… - International Journal of …, 2019 - mdpi.com
… cells. Dendritic cells DCs could play a pivotal role in enhancing the antitumor efficacy of CIKs.
… It was also found that CIK cells treatment had comparable adverse events compared to the …
… It was also found that CIK cells treatment had comparable adverse events compared to the …
Induction of tolerance by IL-10-treated dendritic cells.
K Steinbrink, M Wölfl, H Jonuleit, J Knop… - Journal of immunology …, 1997 - journals.aai.org
… We demonstrate that treatment of immature DC with IL- 10 inhibits the expression of MHC
class 11, the costimulatory molecules CD58 and CD86, and the DC marker Ag CD83. More …
class 11, the costimulatory molecules CD58 and CD86, and the DC marker Ag CD83. More …
Cancer immunotherapy via dendritic cells
K Palucka, J Banchereau - Nature Reviews Cancer, 2012 - nature.com
… Another approach is through vaccination; that is, the provision of an antigen together with
an adjuvant to elicit therapeutic T cells in vivo. Owing to their properties, dendritic cells (DCs) …
an adjuvant to elicit therapeutic T cells in vivo. Owing to their properties, dendritic cells (DCs) …
Understanding dendritic cells and their role in cutaneous carcinoma and cancer immunotherapy
VR Yanofsky, H Mitsui, D Felsen… - Journal of Immunology …, 2013 - Wiley Online Library
… cells (LC), myeloid-derived dermal dendritic cells (mDC) and plasmacytoid dendritic cells
(… This may be relevant for the treatment of squamous cell carcinoma, where we have shown …
(… This may be relevant for the treatment of squamous cell carcinoma, where we have shown …
Dendritic cells in cancer immunology and immunotherapy
… and treatment responsiveness. Although dendritic cells (DCs) constitute a rare immune
cell population within tumours and lymphoid organs, these cells are central for the initiation of …
cell population within tumours and lymphoid organs, these cells are central for the initiation of …