Logical modelling of in vitro differentiation of human monocytes into dendritic cells unravels novel transcriptional regulatory interactions
KJ Nuñez-Reza, A Naldi… - Interface …, 2021 - royalsocietypublishing.org
… (DCs) are the major specialized antigen-presenting cells, … we established a preliminary
logical model that helped us identify … between TFs that compose our final logical model. Figure 3. …
logical model that helped us identify … between TFs that compose our final logical model. Figure 3. …
Logical model of human tolerogenic dendritic cells and their participation in autoimmune disease
KJ Nuñez-Reza, I Lozano-Jiménez… - bioRxiv, 2023 - biorxiv.org
… Here we built a logical model for the tolerization cellular process of dendritic cells using IL10…
and key tolDC markers, we ensembled a logical model that describes the obtention of tolDC …
and key tolDC markers, we ensembled a logical model that describes the obtention of tolDC …
[HTML][HTML] A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery
… Our logical model consists of 281 components that connect … involved in dendritic cells
and antigen-presenting cells, we … : “dendritic cells AND antigen-presenting cell AND MoDC …
and antigen-presenting cells, we … : “dendritic cells AND antigen-presenting cell AND MoDC …
Logical modeling of dendritic cells in vitro differentiation from human monocytes unravels novel transcriptional regulatory interactions
KJ Nuñez-Reza, A Naldi, A Sanchéz-Jiménez… - bioRxiv, 2020 - biorxiv.org
… Monocytes can differentiate into dendritic cells in vitro in the … regulation responsible for
dendritic cell differentiation from … , we established a preliminary logical model that helped us …
dendritic cell differentiation from … , we established a preliminary logical model that helped us …
[HTML][HTML] Multi-level computational Modeling of anti-Cancer dendritic cell vaccination utilized to select molecular targets for therapy optimization
… Dendritic cells (DCs) are the strongest stimulators of our immune response (Fong and …
Finally, we included a model module accounting for T cell activation by DCs in the spleen. The …
Finally, we included a model module accounting for T cell activation by DCs in the spleen. The …
[HTML][HTML] Dynamical Boolean Modeling of Immunogenic Cell Death
… bnd file containing the logical rules and the definition … model. (A) Influence network of the
extended version of ICD involving four cell types: tumor cells (light purple nodes), dendritic cells …
extended version of ICD involving four cell types: tumor cells (light purple nodes), dendritic cells …
Optimal treatment strategies using dendritic cell vaccination for a tumor model with parameter identifiability
… After the introduction, we describe the biological background behind the formulation of the
… antigen representing cells (APCs) in vertebrate immune systems and, in our model, are the …
… antigen representing cells (APCs) in vertebrate immune systems and, in our model, are the …
A multi-compartment hybrid computational model predicts key roles for dendritic cells in tuberculosis infection
S Marino, DE Kirschner - Computation, 2016 - mdpi.com
… computational modeling approach to … dendritic cells as they serve as the link between
physiological compartments of lungs and lymph nodes (LNs) that generate activated immune cells …
physiological compartments of lungs and lymph nodes (LNs) that generate activated immune cells …
Logical modeling of cell fate specification—Application to T cell commitment
… cell differentiation, pattern formation and embryonic development. Here, we describe a logical
modeling … rules specifying the behavior of model components depending on the levels or …
modeling … rules specifying the behavior of model components depending on the levels or …
Modeling Dendritic Cell Pulsed Immunotherapy for Mice with Melanoma—Protocols for Success and Recurrence
JC Chimal-Eguia, E Castillo-Montiel… - Applied Sciences, 2021 - mdpi.com
… The model and parameter are adjusted for the … The model consists of ODE system that
considers interactions between melanoma cells (T), cytotoxic T cells (CTLs), dendritic cells (…
considers interactions between melanoma cells (T), cytotoxic T cells (CTLs), dendritic cells (…
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