Nanovaccine‐Mediated Cell Selective Delivery of Neoantigens Potentiating Adoptive Dendritic Cell Transfer for Personalized Immunization
P Xiao, J Wang, L Fang, Z Zhao, X Sun… - Advanced Functional …, 2021 - Wiley Online Library
… [ 2 ] After a hybrid injection, we find that the nanovaccines enable selective delivery of
neoantigens to resident APCs in LNs. The nanovaccines enhance the secretion of chemokine CC …
neoantigens to resident APCs in LNs. The nanovaccines enhance the secretion of chemokine CC …
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice
A Mukhopadhaya, T Hanafusa… - Proceedings of the …, 2008 - National Acad Sciences
… CD8 + T cells specific for β cell antigens can … , dendritic cells (DCs) present model antigens
in a tolerogenic manner in the steady state, eg, in the absence of infection, and cause T cells …
in a tolerogenic manner in the steady state, eg, in the absence of infection, and cause T cells …
Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes
… with DC recognition molecules for a selective delivery and an increased uptake by DCs,
concomitantly with a decrease of the required dose. DCs express several cell surface receptors, …
concomitantly with a decrease of the required dose. DCs express several cell surface receptors, …
Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses
CY Fan, SW Wang, C Chung, JY Chen, CY Chang… - Chemical …, 2024 - pubs.rsc.org
… selectively deliver the mRNA vaccine to antigen-presenting cells (APCs) especially dendritic
cells, … into the polymer which was evaluated for selective delivery of mRNA to dendritic cells. …
cells, … into the polymer which was evaluated for selective delivery of mRNA to dendritic cells. …
Targeted antigen delivery and activation of dendritic cells in vivo: steps towards cost effective vaccines
PJ Tacken, CG Figdor - Seminars in immunology, 2011 - Elsevier
… dendritic cells (DCs) has been explored in the clinic. Albeit safe, clinical results have thus far
been limited. A major disadvantage of current cell-based dendritic cell (… Targeted delivery of …
been limited. A major disadvantage of current cell-based dendritic cell (… Targeted delivery of …
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
RA Rosalia, LJ Cruz, S van Duikeren, AT Tromp… - Biomaterials, 2015 - Elsevier
… and selective delivery to DC in vivo upon sc injection and improved priming of CD8 + T cells
… We conclude that CD40-mediated delivery to DC of NP-vaccines, co-encapsulating Ag and …
… We conclude that CD40-mediated delivery to DC of NP-vaccines, co-encapsulating Ag and …
Targeting antigens to dendritic cells in vivo
PJ Tacken, R Torensma, CG Figdor - Immunobiology, 2006 - Elsevier
… on the various antigen delivery systems that … dendritic cells (DCs) in vivo for vaccination
purposes depends on a number of factors. First, the efficiency with which the antigen is delivered …
purposes depends on a number of factors. First, the efficiency with which the antigen is delivered …
Selective tumor-specific antigen delivery to dendritic cells using mannose-labeled poly (d, l-lactide-co-glycolide) nanoparticles for cancer immunotherapy
TI Wi, Y Byeon, JE Won, JM Lee… - Journal of …, 2020 - ingentaconnect.com
… In this study, we demonstrate a selective delivery system of tumor-specific antigens to DCs
using MN-PLGA-NPs as a novel vaccine system without ex vivo manipulation. This approach …
using MN-PLGA-NPs as a novel vaccine system without ex vivo manipulation. This approach …
Direct delivery of antigens to dendritic cells via antibodies specific for endocytic receptors as a promising strategy for future therapies
CHK Lehmann, L Heger, GF Heidkamp, A Baranska… - Vaccines, 2016 - mdpi.com
… Therefore, a more DC-specific antigen delivery technique is required. In consideration of
those less specific antigen delivery techniques, the idea arose that a selective delivery of …
those less specific antigen delivery techniques, the idea arose that a selective delivery of …
Antigen delivery by dendritic cells
H Moll - International journal of medical microbiology, 2004 - Elsevier
… Dendritic cells (DC) link the innate and adaptive arms of the immune system and thus orchestrate
the … Selectively delivering antigens to DC in situ, combined with administration of a DC …
the … Selectively delivering antigens to DC in situ, combined with administration of a DC …
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