[HTML][HTML] Structural plasticity of dendritic spines: the underlying mechanisms and its dysregulation in brain disorders

KO Lai, NY Ip - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2013 - Elsevier
… on dendritic spines rather than the dendritic shafts of the postsynaptic neuron? Dendritic
spines likely offer distinct advantages for excitatory neurotransmission and function of the brain

Dendritic spine pathology in neuropsychiatric disorders

P Penzes, ME Cahill, KA Jones, JE VanLeeuwen… - Nature …, 2011 - nature.com
… in dendritic spine shape, size or number accompany a large number of brain disorders,
suggesting that dendritic spines … substrate for many neuropsychiatric disorders, particularly those …

Dendritic spine pathology: cause or consequence of neurological disorders?

JC Fiala, J Spacek, KM Harris - Brain research reviews, 2002 - Elsevier
… The principal neurons of most brain regions are covered with small protrusions known as
dendritic spines. Dendritic spines are the main sites of excitatory synaptic input for these …

The dendritic tree and brain disorders

VA Kulkarni, BL Firestein - Molecular and Cellular Neuroscience, 2012 - Elsevier
… rebuild neural circuitry, newborn neurons need to integrate into the existing neural network
by developing dendrites and dendritic spines to receive and convey information. Therefore, …

Plasticity of dendritic spines: Molecular function and dysfunction in neurodevelopmental disorders

J Nishiyama - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
… between dendritic spine abnormalities and neuropsychiatric disorders was first suggested
by Golgi staining of post-mortem brain … These studies reported two types of dendritic spine

Dendritic spine pathology in neurodegenerative diseases

J Herms, MM Dorostkar - Annual Review of Pathology …, 2016 - annualreviews.org
dendritic spine dysfunction as an important substrate of the pathogenesis of dementia in these
disorders… or indirect structural alterations at dendritic spines in the pathogenesis of major …

Dynamics and pathology of dendritic spines

S Halpain, K Spencer, S Graber - Progress in brain research, 2005 - Elsevier
Dendritic spines are key players in information processing in the brain. Changes in …
development and stabilization may yield insights into mental retardation and psychiatric disorders. …

Structure and function of dendritic spines

EA Nimchinsky, BL Sabatini… - Annual review of …, 2002 - annualreviews.org
… Numerousbrain disorders are associated with abnormal dendritic spines. … This review
focuses on experiments performed on dendritic spines of Purkinjecells of the cerebellum and …

Molecular regulation of dendritic spine dynamics and their potential impact on synaptic plasticity and neurological diseases

P Maiti, J Manna, G Ilavazhagan, J Rossignol… - Neuroscience & …, 2015 - Elsevier
… with several psychiatric disorders, including autism spectrum disorders, schizophrenia, … the
dynamics of dendritic spines. As such dendritic spines are vital for our higher brain functions, …

Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models

V Martínez‐Cerdeño - Developmental neurobiology, 2017 - Wiley Online Library
… of neuronal dendrites and dendritic spines in autism and related disorders. Although there
… Here, we review how dendrite and spine morphology and number is affected in autism and …