Structure and physiologic function of the low-density lipoprotein receptor

H Jeon, SC Blacklow - Annu. Rev. Biochem., 2005 - annualreviews.org
… The receptor binds lipoproteinreceptor dictate the binding of low-density lipoprotein (LDL)
and beta-migrating forms of very low-density lipoprotein (β-VLDL) particles, how the receptor

Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders

JL Mehta, J Chen, PL Hermonat, F Romeo… - Cardiovascular …, 2006 - academic.oup.com
LOX-1, a lectin-like 52-kD receptor for oxidized low-density lipoproteins (ox-LDL), is present
primarily on endothelial cells. This receptor is upregulated by ox-LDL itself and by …

The mammalian low-density lipoprotein receptor family

MM Hussain, DK Strickland… - Annual review of …, 1999 - annualreviews.org
… (LDL-R) family consists of cell-surface receptors that recognize extracellular ligands and …
contains very-low-density lipoprotein receptors (VLDL-R), apolipoprotein E receptor 2, LRP, …

The low density lipoprotein receptor

WJ Schneider - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1989 - Elsevier
… In this mnitistep mechanism, bepatically derived nascent high density lipoprotein (HDL)
particles interact with cells in peripheral tissues and pick up epIhdar ehntegternl Receptor~ …

The very low-density lipoprotein (VLDL) receptor: characterization and functions as a peripheral lipoprotein receptor

S Takahashi, J Sakai, T Fujino, H Hattori… - … of atherosclerosis and …, 2004 - jstage.jst.go.jp
density lipoprotein receptor-A second lipoprotein receptor … of the human very low density
lipoprotein receptor gene. J Biol … overexpressing very low density lipoprotein receptor. Biochem …

Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor–deficient mice

L Gu, Y Okada, SK Clinton, C Gerard, GK Sukhova… - Molecular cell, 1998 - cell.com
… Monocyte chemoattractant protein-1 (MCP-1), a CC chemokine, is one likely signal involved
in this process. To test MCP-1’s role in atherogenesis, low density lipoprotein (LDL) receptor

Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions

H Kataoka, N Kume, S Miyamoto, M Minami… - Circulation, 1999 - Am Heart Assoc
… identified a novel receptor for Ox-LDL, designated C-type lectinlike Ox-LDL receptor-1 (LOX-1),
in … Characterization of a receptor for oxidized low-density lipoproteins on rat Kupffer cells: …

Low-density lipoprotein receptor-its structure, function, and mutations

JC Defesche - Seminars in vascular medicine, 2004 - thieme-connect.com
… Localization of low density lipoprotein receptors on plasma membrane of normal human
fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote. Proc …

Low-density lipoprotein receptor–related protein-1: role in the regulation of vascular integrity

DK Strickland, DT Au, P Cunfer… - … , and vascular biology, 2014 - Am Heart Assoc
Low-density lipoprotein receptor–related protein-1 (LRP1) is a large endocytic and signaling
receptor that is widely expressed. In the liver, LRP1 plays an important role in regulating the …

Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice

D Praticò, C Tillmann, ZB Zhang, H Li… - Proceedings of the …, 2001 - National Acad Sciences
… Because deletion of the PGI 2 receptor accelerates atherogenesis in the fat-fed low density
lipoprotein receptor knockout mouse, we wished to determine whether selective inhibition of …