Claudin-1 decrease impacts epidermal barrier function in atopic dermatitis lesions dose-dependently

S Bergmann, B von Buenau, S Vidal-y-Sy, M Haftek… - Scientific reports, 2020 - nature.com
… Because it was shown in mice that loss of Cldn-1 increased the expression of the pro-inflammatory
cytokine IL-1β 15 dose-dependently, we tested whether the loss of Cldn-1 resulted in …

[PDF][PDF] Possible antipruritic mechanism of cyclosporine A in atopic dermatitis

KC Ko, M Tominaga, Y Kamata… - Acta dermato …, 2016 - medicaljournalssweden.se
… Atopic dermatitis (AD) is a relapsing chronic inflammatory skin disease characterized by …
expression were inhibited dosedependently in the CsA-treated group, especially at a dose of 5 …

[HTML][HTML] Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect

SJ Brown, K Kroboth, A Sandilands… - Journal of Investigative …, 2012 - Elsevier
dermatitis cases were compared with 928 population controls to test the hypothesis that CNV
within FLG affects the risk of atopic dermatitis independently of … 31 atopic dermatitis patients …

A randomized double‐blinded placebo‐controlled study to evaluate an effective ciclosporin dose for the treatment of feline hypersensitivity dermatitis

S King, C Favrot, L Messinger, T Nuttall… - Veterinary …, 2012 - Wiley Online Library
… , including a composite lesion score similar to the canine atopic dermatitis extent and severity
… Each lesion type (E, MD, EP and SA) was scored independently. A numerical rating scale …

[HTML][HTML] Semaphorin3A alleviates skin lesions and scratching behavior in NC/Nga mice, an atopic dermatitis model

J Yamaguchi, F Nakamura, M Aihara… - Journal of Investigative …, 2008 - Elsevier
… are commonly used for the treatment of atopic dermatitis (AD). However, in a … the skin lesions
of NC/Nga mice, an animal model of AD. Sema3A dose-dependently improved skin lesions

Development of new atopic dermatitis models characterized by not only itching but also inflammatory skin in mice

R Yatsuzuka, T Inoue, S Jiang, Y Nakano… - European journal of …, 2007 - Elsevier
… Naloxone dose-dependently reduced the frequency of scratching in the last stage. Moreover…
Atopic dermatitis is a chronic inflammatory skin disease with itching, and many patients with …

Oral administration of dihomo-γ-linolenic acid prevents development of atopic dermatitis in NC/Nga mice

H Kawashima, N Tateishi, A Shiraishi, N Teraoka… - Lipids, 2008 - Springer
… of dermatitis in NC/Nga mice, which spontaneously develop human AD-like skin lesions.
NC/… DGLA suppressed clinical severity of skin lesions dose-dependently, with an increase in …

Low-dose ethanol aggravates allergic dermatitis in mice

F Sakazaki, H Ogino, T Arakawa, T Okuno, H Ueno - Alcohol, 2014 - Elsevier
… ethanol enhances the expression of inflammatory cytokines independently from T helper (Th)1/…
dermatitis are usually chronic whereas the mouse models are acute. Therefore, a chronic

Effects of metronidazole and tinidazole ointments on models for inflammatory dermatitis in mice

K Nishimuta, Y Ito - Archives of dermatological research, 2003 - Springer
… human atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by chronic
… In contrast, FK506 ointment (0.1%) dose-dependently suppressed both the IPR and LPR in …

Anti‐IL‐31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice

K Kasutani, E Fujii, S Ohyama, H Adachi… - British Journal of …, 2014 - Wiley Online Library
… The anti-IL-31 receptor α-neutralizing antibody reduced the ear swelling and dermatitis
score in a chronic pruritus-inducing AD-like model. Moreover, treatment with the anti-IL-31 …