Drug delivery techniques for buccal route: formulation strategies and recent advances in dosage form design

S Barua, H Kim, K Jo, CW Seo, TJ Park, KB Lee… - Journal of …, 2016 - Springer
… Therefore, an impermeable backing layer has been designed in buccal tablet formulations
to improve the drug residency in buccal mucosa. Using this technology, various scientists …

Quality by Design-Guided Systematic Development and Optimization of Mucoadhesive Buccal Films

AAA Hassan, K Kristó, YHEY Ibrahim, G Regdon Jr… - Pharmaceutics, 2023 - mdpi.com
… In the present study, comprehensive research was performed to identify and understand
how different CMAs and CPPs of the casting method influence the formulation of buccal films. …

[HTML][HTML] Buccal films: A review of therapeutic opportunities, formulations & relevant evaluation approaches

L Shipp, F Liu, L Kerai-Varsani, TC Okwuosa - Journal of Controlled …, 2022 - Elsevier
… with no authorised mucoadhesive buccal films available in the … of the mucoadhesive buccal
film technology and identify key … films was provided, highlighting manufacturing methods like …

New formulation and approach for mucoadhesive buccal film of rizatriptan benzoate

S Salehi, S Boddohi - Progress in biomaterials, 2017 - Springer
… to design a new formulation of RB mucoadhesive buccal film … and freeze-dried buccal film
formulation with and without RB … and other components of film formulation. Each sample was …

… of composition on mechanical and physicochemical properties of mucoadhesive buccal films containing buprenorphine hydrochloride: From design of experiments to …

Z Kazemi, SM Taghizadeh, ST Keshavarz… - Journal of Drug Delivery …, 2020 - Elsevier
… Using this method, it … composition of BUP-containing mucoadhesive buccal film on mechanical
and physicochemical of prepared films using DOE, able to adhere adequately to the oral

Quality by design approach in the formulation of glibenclamide mucoadhesive buccal films

SS Shaikh, A Barrawaz - Analytical Chemistry Letters, 2021 - Taylor & Francis
… The main aim of the present work was to develop a mucoadhesive buccal film by applying
the QbD approach. GLB belongs to BCS class II drugs (Low solubility, High permeability). The …

Risperidone mucoadhesive buccal tablets: formulation design, optimization and evaluation

B Çelik - Drug design, development and therapy, 2017 - Taylor & Francis
… The purpose of this study was to develop buccal tablet formulations of RIS for the first time
to be used as an alternative delivery system in the treatment of schizophrenia. Screening …

An updated overview of the emerging role of patch and film-based buccal delivery systems

S Jacob, AB Nair, SHS Boddu, B Gorain, N Sreeharsha… - Pharmaceutics, 2021 - mdpi.com
… of buccal films are briefed. Ongoing and completed clinical trials of buccal film formulations
designed … nanocarriers incorporated in buccal film to resolve potential formulation and drug-…

Design and development of a mucoadhesive buccal film bearing progesterone

SK Jain, A Jain, Y Gupta… - Die Pharmazie-An …, 2008 - ingentaconnect.com
… 9.21 Æ 0.051 to 9.67 Æ 0.086 mg/cm2 for formulation F1 to F4. Maximum bioadhesion force
was recorded for PVP buccal films (formulation F2) ie 0.45 Æ 0.53 N as compared to other …

Quality by design (QbD) assisted fabrication of fast dissolving buccal film for clonidine hydrochloride: Exploring the quality attributes

PV Dangre, RD Phad, SJ Surana… - Advances in Polymer …, 2019 - Wiley Online Library
Design of experimentation (DoE) is a systematic study to determine the interaction between
… of final formulation. In the present study, a 3 2 full factorial design approach was utilized to …