DNA methylation as a noninvasive epigenetic biomarker for the detection of cancer

C Leygo, M Williams, HC Jin, MWY Chan… - Disease …, 2017 - Wiley Online Library
… summarise current knowledge on methylated DNA and its implications in cancer to explore
its … with higher accuracy and more effective detection methods will enable improved clinical …

DNA methylation and cancer diagnosis

Y Delpu, P Cordelier, WC Cho, J Torrisani - International journal of …, 2013 - mdpi.com
detection and the discovery of aberrantly methylated DNADNA methylation studies. We
discuss the interest and perspectives on the use of DNA methylation measurements for cancer

Sensitive detection of DNA methylation

SE Cottrell, PW Laird - Annals of the New York Academy of …, 2003 - Wiley Online Library
… be capable of detecting the methylation of only a few nanograms of DNA. Diagnostic markers
that are based on DNA methylation are particularly well suited for cancer detection for the …

DNA methylation and cancer diagnosis: new methods and applications

P Dehan, G Kustermans, S Guenin… - Expert review of …, 2009 - Taylor & Francis
… this stability through mitosis is DNA methylation. DNA methylation is a chemical modification
… , the epigenetic research moved toward methods that detect methylation on a large scale in …

Use of DNA methylation for cancer detection and molecular classification

J Zhu, X Yao - BMB Reports, 2007 - koreascience.kr
… Therefore, our efforts to establish a DNA methylated method to detect bladder cancer in …
cancer cell lines, bladder cancer tissues and urine sediments. Then 21 genes were methylated

Use of DNA methylation for cancer detection: promises and challenges

J Zhu, X Yao - The international journal of biochemistry & cell biology, 2009 - Elsevier
… assessed for cancer diagnosis … DNA methylation as a biomarker for cancer prognosis. Both
the promises and challenges to realizing the clinical utility of the DNA methylation in cancer

Analysis of DNA methylation status in bodily fluids for early detection of cancer

K Yokoi, K Yamashita, M Watanabe - International journal of molecular …, 2017 - mdpi.com
Detection of DNA methylation in bodily fluids using classical methods such as quantitative
methylation … In this article, we reviewed studies that analyzed DNA methylation in less-…

DNA methylation markers for early detection of women's cancer: promise and challenges

T Wittenberger, S Sleigh, D Reisel, M Zikan, B Wahl… - …, 2014 - Taylor & Francis
… A DNA methylation (DNAme) signature identified in serum cell-free DNA from patients …
Consequently, a major hurdle for the identification of early detection cancer biomarkers has …

DNA methylation-based point-of-care cancer detection: challenges and possibilities

AAI Sina, LG Carrascosa, M Trau - Trends in molecular medicine, 2019 - cell.com
… Recent advances in methylation analysis provide a more precise … of DNA methylation
changes towards cancer progression. Consequently, the discoveries of numerous methylation-…

Cervical cancer detection by DNA methylation analysis in urine

BC Snoek, AP Splunter, MCG Bleeker, MC Ruiten… - Scientific reports, 2019 - nature.com
… best suited for hrHPV detection and DNA methylation analysis we analyzed paired urine
sediments and native urine from 28 women with cervical cancer. HrHPV was detected in 25 (89…