Mutation-Specific Antibodies for the Detection of EGFR Mutations in Non–Small-Cell Lung Cancer

J Yu, S Kane, J Wu, E Benedettini, D Li, C Reeves… - Clinical Cancer …, 2009 - AACR
mutations. To develop a simple, sensitive, and reliable … of EGFR mutations in NSCLC patients,
we generated mutation-specific … EGFR mutations and aimed to evaluate the detection of …

Worldwide Frequency of Commonly Detected EGFR Mutations

RP Graham, AL Treece, NI Lindeman… - … of pathology & …, 2018 - meridian.allenpress.com
… In conclusion, we provide results from the CAP proficiency testing on EGFR mutation
analysis that indicate the relative detection rate of EGFR mutations. Although not truly …

Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

S Maheswaran, LV Sequist, S Nagrath… - … England Journal of …, 2008 - Mass Medical Soc
… SARMS assay 23 for detecting EGFR mutations in rare cell populations. This test is designed
to detect multiple drug sensitivity-associated types of EGFR mutation, including the multiple …

Immunohistochemical Detection of EGFR Mutation Using Mutation-Specific Antibodies in Lung Cancer

A Kitamura, W Hosoda, E Sasaki, T Mitsudomi… - Clinical Cancer …, 2010 - AACR
… reaction to mutation-specific antibodies differs from the molecular EGFR mutation. Therefore,
… all patients with EGFR mutations can be selected using these mutation-specific antibodies. …

Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer

S Simonetti, MA Molina, C Queralt, I de Aguirre… - Journal of translational …, 2010 - Springer
mutation-specific mAbs against EGFR is a promising method for detecting EGFR mutations
in … possible role in routine clinical practice for screening EGFR mutations in NSCLC patients. …

Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas

K Taniguchi, J Uchida, K Nishino, T Kumagai… - Clinical cancer …, 2011 - AACR
… BEAMing to detect activating and resistant EGFR mutations in … lesions as a source of EGFR
mutation detection. Its major advantage … during EGFR-TKI therapy via the T790M mutation. …

Detection of EGFR Gene Mutation in Lung Cancer by Mutant-Enriched Polymerase Chain Reaction Assay

H Asano, S Toyooka, M Tokumo, K Ichimura, K Aoe… - Clinical Cancer …, 2006 - AACR
EGFR mutants (19), because the presence of amplified mutant genes should increase the
possibility of detection. Indeed, our mutant-enriched PCR assay detected EGFR alterations …

A Novel Technique to Detect EGFR Mutations in Lung Cancer

Y Liu, T Lei, Z Liu, Y Kuang, J Lyu, Q Wang - International journal of …, 2016 - mdpi.com
… with Our Novel Detection Technique In this study, we detected EGFR mutations in cell lines
… technique, and the data confirmed EGFR mutations in these NSCLC cell lines that matched …

Diagnostic value of circulating free DNA for the detection of EGFR mutation status in NSCLC: a systematic review and meta-analysis

J Luo, L Shen, D Zheng - Scientific Reports, 2014 - nature.com
… In conclusion, in our meta-analysis of 20 studies including >2000 participants, detection
EGFR mutations in cfDNA appears to be of adequate diagnostic value in NSCLC. Due to its high …

Detection of EGFR mutations in plasma DNA from lung cancer patients by mass spectrometry genotyping is predictive of tumor EGFR status and response to EGFR …

M Brevet, ML Johnson, CG Azzoli, M Ladanyi - Lung cancer, 2011 - Elsevier
… to EGFR TKI [3], [5], [6], [7], [9]. In this study, we report the detection of EGFR L858R mutations
and EGFR … The detection of these mutations in plasma samples is correlated with better …