… stress and a decrease of insulin production that are responsible for the development of diabetes
and progression … misfolding and ER stress in the development and progression of type 2 …

… to determine more precisely the extent to which the UPR is activated in lesional SMCs during
lesion development and how ER-stressed SMCs might affect atherosclerosis progression. …

The early steps of insulin biosynthesis occur in the endoplasmic reticulum (ER), and the β-cell
has a highly developed and active ER. All cells regulate the capacity of their ER to fold …

… development, neuroprotection, and cancer progression. Abbreviations: N, nucleus; ER,
endoplasmic reticulum… is a major contributor to tumor progression such that partial reduction of …

… roles in the development and progression of cardiovascular diseases, … In this review, we
summarize the recent progress in … increasing health burden in developed countries. Thus, the …

… In acute and chronic kidney disease, ER stress contributes to the development and
progression of glomerular and tubular disease. Accumulating evidence suggests the possibility of …

… However, prolonged ER stress will lead to cell dysfunction and apoptosis. Recent evidence
revealed that ER stress is involved in the development and progression of various heart …

… reticulum stress in the initiation and progression of atherosclerosis and discuss possible
strategies to target this pathway toward the development of new anti-atherogenic therapies. …

… In this mini review, we outline the role of ER stress and the UPR process in the development
and progression of disease, because a better understanding of cell survival and apoptotic …

… to prevent the development and progression of type 2 diabetes is the inhibition of ER stress.
… therapeutic strategies to block the development and the progression of diabetic retinopathy. …