Development of curcumin as an epigenetic agent

S Fu, R Kurzrock - Cancer, 2010 - Wiley Online Library
… This review summarizes the current data surrounding curcumin-mediated epigenetic
modulation … for curcumin's promise as an epigenetic agent for cancer therapy drug development. …

Curcumin as a regulator of epigenetic events

MH Teiten, M Dicato, M Diederich - Molecular nutrition & food …, 2013 - Wiley Online Library
… balance recently became an attractive approach to develop new strategies in cancer … ,
appears as an interesting epigenetic agent 31-33. Curcumin or diferuloylmethane, extracted from …

[HTML][HTML] Epigenetic changes induced by curcumin and other natural compounds

S Reuter, SC Gupta, B Park, A Goel, BB Aggarwal - Genes & nutrition, 2011 - Springer
… The development of curcumin for clinical use as a regulator of epigenetic changes, however,
… such as curcumin have great potential as epigenetic agents. Unlike genetic changes, …

Epigenetic effects of curcumin in cancer prevention

MK Shanmugam, F Arfuso, JC Sng, A Bishayee… - Epigenetics of cancer …, 2019 - Elsevier
… serving as a chemopreventive agent. Among these curcumin-induced epigenetic alterations
is … In addition to their pivotal role in the development of an organism, deregulated epigenetic

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
… of curcumin by development of novel curcumin analogs with … for curcumin, and combination
therapy of curcumin with other … Curcumin is reportedly a potent DNA hypomethylation agent

[HTML][HTML] Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects

F Hassan, MS Rehman, MS Khan, MA Ali… - Frontiers in …, 2019 - frontiersin.org
… The development of curcumin as a clinical … two agents in a sequential way. The sequential
release of both of these hypo-methylating agents maximized epigenetic activity of curcumin for …

[HTML][HTML] Curcumin, the king of spices”: epigenetic regulatory mechanisms in the prevention of cancer, neurological, and inflammatory diseases

SSS Boyanapalli, ANT Kong - Current pharmacology reports, 2015 - Springer
… plays a major role in AML development. However, the mechanism by which … curcumin is a
potent epigenetic regulatory agent in many solid tumors. As a potent DNMT inhibitor, curcumin

Curcumin and its analogs as potential epigenetic modulators: Prevention of diabetes and its complications

C Tang, Y Liu, S Liu, C Yang, L Chen, F Tang, F Wang… - Pharmacology, 2022 - karger.com
epigenetic modulators of curcumin and analogs for prevention of metabolic diseases, and
accelerate development of … studies demonstrated that curcumin is a hypomethylation agent [37-…

[HTML][HTML] Curcumin as an epigenetic therapeutic agent in myelodysplastic syndromes (Mds)

X Xie, D Frank, PK Patnana, J Schütte… - International Journal of …, 2021 - mdpi.com
… of myeloid and lymphoid cell lineages and was implicated in the development of … leads
to epigenetic changes in human and murine AML blasts and accelerated the development of …

Curcumin and dimethoxycurcumin induced epigenetic changes in leukemia cells

HE Hassan, S Carlson, I Abdallah, T Buttolph… - Pharmaceutical …, 2015 - Springer
Curcumin is an ideal chemopreventive and antitumor agent characterized by poor
bioavailability and low stability. The development of synthetic structural analogues like …