Inflammatory bowel disease: cause and immunobiology

DC Baumgart, SR Carding - The Lancet, 2007 - thelancet.com
colitis and Crohn's disease represent the two main types of inflammatory bowel disease. In
… The genetic contribution to the development of inflammatory bowel disease seems, therefore…

Development of inflammatory bowel disease is linked to a longitudinal restructuring of the gut metagenome in mice

T Sharpton, S Lyalina, J Luong, J Pham, EM Deal… - Msystems, 2017 - Am Soc Microbiol
… linked to inflammatory bowel disease (IBD) severity and altered in late-stage disease. However,
it is unclear how gut microbial communities change over the course of IBD development, …

The role of the environment in the development of pediatric inflammatory bowel disease

A Aujnarain, DR Mack, EI Benchimol - Current gastroenterology reports, 2013 - Springer
… The incidence of inflammatory bowel disease (IBD) is rising worldwide, with a particularly …
inflammatory bowel disease development, with focus on pediatric exposures and disease

[HTML][HTML] The Role of Environmental and Nutritional Factors in the Development of Inflammatory Bowel Diseases: A Case–Control Study

V Serrano-Fernandez, JA Laredo-Aguilera… - Nutrients, 2024 - mdpi.com
Background: The incidence and prevalence of inflammatory bowel diseases (IBD) are
increasing around the world, especially in Western countries. The objective of this study was to …

Exposure to oral contraceptives increases the risk for development of inflammatory bowel disease: a meta-analysis of case-controlled and cohort studies

R Ortizo, SY Lee, ET Nguyen, MM Jamal… - European journal of …, 2017 - journals.lww.com
… to the development of inflammatory bowel disease (IBD). The intent of this meta-analysis is
to better define the association between OCP exposure and the risk for development of IBD. …

Epigenetics and the developmental origins of inflammatory bowel diseases

R Kellermayer - Canadian Journal of Gastroenterology and …, 2012 - Wiley Online Library
… The gut microbiota, the intestinal mucosa and the host immune system are among the large
biological networks involved in the development of inflammatory bowel disease (IBD), which …

Drug development in inflammatory bowel disease: the role of the FDA

C Lahiff, S Kane, AC Moss - Inflammatory bowel diseases, 2011 - academic.oup.com
All medicinal compounds sold in the United States for inflammatory bowel disease (IBD) are
regulated by the Food and Drug Administration (FDA) via a number of regulations dating …

[HTML][HTML] The fundamental basis of inflammatory bowel disease

W Strober, I Fuss, P Mannon - The Journal of clinical …, 2007 - Am Soc Clin Investig
Two broad hypotheses have arisen regarding the fundamental nature of the pathogenesis
of inflammatory bowel diseases (IBDs, which include ulcerative colitis and Crohn disease). …

[HTML][HTML] Environmental risk factors for inflammatory bowel disease

AN Ananthakrishnan - Gastroenterology & hepatology, 2013 - ncbi.nlm.nih.gov
… The gut microbiome is a key component in the development of inflammatory bowel disease
(IBD). Several external factors potentially exert an effect by influencing the composition of the …

Sphingosine-1-phosphate metabolism and its role in the development of inflammatory bowel disease

T Wollny, M Wątek, B Durnaś, K Niemirowicz… - International journal of …, 2017 - mdpi.com
… Ulcerative colitis (UC) and Crohn’s disease (CD) represent two principal manifestations
of inflammatory bowel disease (IBD), a chronic inflammatory disorder of the digestive tract [1]. …