The role of the dorsal root ganglion in the development of neuropathic pain

ES Krames - Pain Medicine, 2014 - academic.oup.com
… The dorsal root ganglion (DRG), in the not too distant past, … in the development of abnormal
aberrent neuropathic pain (NP), … , organ, in the process of the development of chronic pain. …

Are voltage-gated sodium channels on the dorsal root ganglion involved in the development of neuropathic pain?

W Wang, J Gu, YQ Li, YX Tao - Molecular pain, 2011 - journals.sagepub.com
root ganglion. We also review evidence regarding changes in their expression under
neuropathic pain conditions and their roles in behavioral responses in a variety of neuropathic pain

The dorsal root ganglion in the pathogenesis of chronic neuropathic pain

D Guha, MF Shamji - Neurosurgery, 2016 - journals.lww.com
… As we have seen, growth factors and proinflammatory cytokines play significant roles in …
or nerve growth factor have been shown to reverse experimentally induced neuropathic pain in …

… of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of neuropathic pain

T Tanaka, M Minami, T Nakagawa, M Satoh - Neuroscience research, 2004 - Elsevier
ganglion (Schreiber et al., 2001). However, the production of MCP-1 in the sensory neurons
in animal models of neuropathic pain … dorsal root ganglia (DRG) of neuropathic pain model …

Dorsal root ganglion–a potential new therapeutic target for neuropathic pain

D Sapunar, S Kostic, A Banozic, L Puljak - Journal of pain research, 2012 - Taylor & Francis
… These findings provide further support for the idea that localized inflammation at the level
of the DRG is an important component in neuropathic pain development. Citation22 …

The roles of T-type calcium channel in the development of neuropathic pain following chronic compression of rat dorsal root ganglia

XJ Wen, SY Xu, ZX Chen, CX Yang, H Liang, H Li - Pharmacology, 2010 - karger.com
… in the development of allodynia and hyperalgesia in the chronic compression of dorsal root
ganglion (CCD) rat model of neuropathic pain. … of T-type Ca2+ channels in neuropathic pain. …

Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain

HS Xiao, QH Huang, FX Zhang, L Bao… - Proceedings of the …, 2002 - National Acad Sciences
… Taken together, current knowledge suggests that changes in gene expression in DRGs
may contribute to the generation and development of neuropathic pain. However, although in …

Pannexin-1 up-regulation in the dorsal root ganglion contributes to neuropathic pain development

Y Zhang, G Laumet, SR Chen, WN Hittelman… - Journal of Biological …, 2015 - ASBMB
… in the dorsal root ganglion (DRG) in the development of chronic neuropathic pain. In this study,
… mechanism involved in increased Panx1 expression in the DRG after nerve injury. Spinal …

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

X Yu, H Liu, KA Hamel, MG Morvan, S Yu, J Leff… - Nature …, 2020 - nature.com
… To determine whether the increase in DRG macrophages contributes to neuropathic pain
development, we chose the MAFIA transgenic line 22 , which as noted above, expresses GFP …

Oxaliplatin Depolarizes the IB4 Dorsal Root Ganglion Neurons to Drive the Development of Neuropathic Pain Through TRPM8 in Mice

B Wu, X Su, W Zhang, YH Zhang, X Feng… - Frontiers in Molecular …, 2021 - frontiersin.org
… or TRPM8 prevented oxaliplatin-induced neuropathic pain behaviors. There results suggest
that … drives that contribute to the development of oxaliplatin-induced neuropathic pain. …